CT findings of 132 patients with cerebral cysticercosis were analysed. The most common finding was multiple parenchymal punctate calcifications, accounting for 53 per cent; calcifications mostly scattered in both cerebral hemispheres. The second most common finding was enhancing ring(s) or nodule(s) of about 1 cm in diameter with perifocal edema, about 43 per cent. Other findings included thin-walled parenchymal cysts of various sizes from less than 1 cm to 7 cm in diameter, non-enhancing low-density area, intraventricular and cisternal cysts, and hydrocephalus due to obstruction of cerebrospinal fluid pathway by the cyst, arachnoiditis, or ependymitis. About 30 per cent of patients had a combination of these forms of cysticercosis. Seizure disorder was the most common presenting symptom. Praziquantel was used effectively in parenchymal cystic forms but without response in intraventricular and cisternal cysts. In conclusion, CT is considered to be the procedure of choice for the detection of cerebral cysticercosis and the follow-up of patients after medical or surgical treatment. When multiple forms of cysticercosis are present, the diagnosis can usually be made with accuracy. A single finding of non-specific pattern such as enhancing ring or nodule, low-density area, or parenchymal cyst(s) without typical mural nodules, has to be differentiated from other conditions such as tumors and inflammatory process. Clinical correlation and follow-up scan are required in these cases in which the definitive diagnosis cannot be ascertained, and in certain cases, surgical intervention may be necessary.
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Cureus
January 2025
Anesthesiology, Universidad Abierta Interamericana, Buenos Aires, ARG.
The differentiation between benign and malignant brain lesions remains a fundamental challenge in modern neuroimaging. This case highlights a rare presentation of ectatic Virchow-Robin spaces (VRS), which mimicked tumefactive brain lesions and required a comprehensive diagnostic evaluation to exclude neoplastic, infectious, and inflammatory processes. A 37-year-old female presented with progressive headache, cognitive impairment, and facial pain.
View Article and Find Full Text PDFAm J Trop Med Hyg
January 2025
Department of Environmental Biology & Medical Parasitology, Hanyang University College of Medicine, Seoul, Republic of Korea.
Neurocysticercosis, a central nervous system infection caused by the zoonotic parasite Taenia solium, is a leading cause of acquired epilepsy worldwide. It is common in areas with extensive pig farming and pork consumption. This report presents an unusual case of neurocysticercosis in a 28-year-old male from Timor-Leste, a region of nonendemicity for human cases of Taenia solium.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.
Albendazole serves as a broad-spectrum anthelmintic medication for treating hydatid cysts and neurocysticercosis. However, its therapeutic effectiveness is limited by poor solubility. Nanocrystals offer a promising technology to address this limitation by enhancing drug solubility.
View Article and Find Full Text PDFPol J Radiol
November 2024
St. Johns Medical College Hospital, Bangalore, India.
Purpose: To study the distinct imaging characteristics of parenchymal neurocysticercosis (NCC) that aid in distinguishing it from other diseases.
Material And Methods: Two hundred fifty patients with NCC were selected based on identification of the scolex. T2 weighted, T1 fluid attenuated inversion recovery (FLAIR), T2 FLAIR, susceptibility weighted imaging, constructive interference in steady state, diffusion weighted imaging, and T1 weighted contrast sequences were performed.
J Med Case Rep
December 2024
Department of General Medicine, INHS Asvini, Mumbai, India.
Background: Cysticercosis, a parasitic infection caused by the larval stages of the pork tapeworm, Taenia solium, predominantly affects cerebral and ocular tissues. The subcutaneous manifestation of this disease is a relatively uncommon clinical occurrence. Previously very few or no cases of cysticercosis presenting as subcutaneous solitary painful swelling have been reported in the literature.
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