Therapy: Risk of metformin use in patients with T2DM and advanced CKD.

Nat Rev Endocrinol

Clinical Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

Published: December 2015

In a new study published in The Lancet Diabetes & Endocrinology, metformin use is associated with significantly increased all-cause mortality in patients with type 2 diabetes mellitus and stage 5 chronic kidney disease (CKD). The findings support current recommendations that metformin should not be used in patients with stage 5 CKD.

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Source
http://dx.doi.org/10.1038/nrendo.2015.132DOI Listing

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