The spatial positioning of 3D tumor-mimetic microenvironments, containing multiple cell types, is controlled with a simple concentric flow device in a single step. A range of geometric architectures are demonstrated, and the migration of segregated tumor cells and macrophages is explored using drugs that inhibit heterotypic interactions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745120 | PMC |
| http://dx.doi.org/10.1002/adma.201501729 | DOI Listing |
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