AI Article Synopsis
- Internal urethrotomy is used in female patients to prevent recurrent bacterial cystitis and manage sterile dysuric voiding disorders.
- 72% of women treated for bacterial cystitis remained uninfected in the year following the procedure.
- 60% of women with sterile dysuria experienced significant improvement, suggesting benefits from better urodynamic conditions, though the exact cause of sterile dysuric voiding disorders is still unknown.
Article Abstract
Internal urethrotomy is still used in female patients for the prophylactic treatment of recurrent bacterial cystitis as well as for sterile dysuric voiding disorders. 72% of the bacterial cystitis group (n = 18) remained uninfected during the 1st year after the treatment. 60% of the women with sterile dysuria complaints reported a significant improvement after the surgical procedure. The success is most possibly due to improved urodynamic conditions. The necessity of urethrotomy in patients with recurrent bacterial cystitis is discussed. The etiology of sterile dysuric voiding disorders however remains unclear.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Follicular Cystitis, a Rare Diagnosis in an Emergency Setting: A case report and literature review.
Int J Surg Case Rep
December 2024
Urology A Department, University Hospital IBN SINA, Morocco.
Introduction And Importance: Follicular cystitis (FC) is a rare inflammatory disorder of the bladder that predominantly affects women. The exact cause of FC remains largely unknown, although it has been associated with inflammatory processes and bacterial infections, particularly following urinary tract infections. Regarding orphan diseases, like follicular cystitis, where large-scale trials seem virtually impossible, case reports find their place and guide the scientific community to find the best course of action.
View Article and Find Full Text PDFAre causing recurrent cystitis just ordinary uropathogenic (UPEC) strains?
Virulence
December 2025
Department of Infectious Diseases, Univ Rouen Normandie, Université de Caen Normandie, INSERM, Normandie Univ, DYNAMICURE UMR 1311, CHU Rouen, Rouen, France.
Specific determinants associated with Uropathogenic (UPEC) causing recurrent cystitis are still poorly characterized. Using strains from a previous clinical study (Vitale study, clinicaltrials.gov, identifier NCT02292160) the aims of this study were (i) to describe genomic and phenotypic traits associated with recurrence using a large collection of recurrent and paired sporadic UPEC isolates and (ii) to explore within-host genomic adaptation associated with recurrence using series of 2 to 5 sequential UPEC isolates.
View Article and Find Full Text PDFNeutrophil NADPH oxidase promotes bacterial eradication and regulates NF-κB-Mediated inflammation via NRF2 signaling during urinary tract infections.
Mucosal Immunol
December 2024
Kidney and Urinary Tract Center, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA; Division of Nephrology and Hypertension, Nationwide Children's Hospital, Columbus, OH 43215, USA. Electronic address:
The precise role of neutrophil-derived reactive oxygen species (ROS) in combating bacterial uropathogens during urinary tract infections (UTI) remains largely unexplored. In this study, we elucidate the antimicrobial significance of NADPH oxidase 2 (NOX2)-derived ROS, as opposed to mitochondrial ROS, in facilitating neutrophil-mediated eradication of uropathogenic Escherichia coli (UPEC), the primary causative agent of UTI. Furthermore, NOX2-derived ROS regulate NF-κB-mediated inflammatory responses in neutrophils against UPEC by inducing the release of nuclear factor erythroid 2-related factor 2 (Nrf2) from its inhibitor, Kelch-like ECH-associated protein 1 (Keap1).
View Article and Find Full Text PDFEffect of a Feedback Visit and a Clinical Decision Support System Based on Antibiotic Prescription Audit in Primary Care: Multiarm Cluster-Randomized Controlled Trial.
J Med Internet Res
December 2024
Department of General Practice, Faculty of Medicine, Nantes University, Nantes, France.
Background: While numerous antimicrobial stewardship programs aim to decrease inappropriate antibiotic prescriptions, evidence of their positive impact is needed to optimize future interventions.
Objective: This study aimed to evaluate 2 multifaceted antibiotic stewardship interventions for inappropriate systemic antibiotic prescription in primary care.
Methods: An open-label, cluster-randomized controlled trial of 2501 general practitioners (GPs) working in western France was conducted from July 2019 to January 2021.
Persistent Elevation in Urinary Neutrophil Gelatinase-Associated Lipocalin Levels Can Be a Predictor of Urinary Tract Infection Recurrence or Persistence in Women.
Int J Mol Sci
November 2024
Department of Urology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, and Tzu Chi University, Hualien 970, Taiwan.
Women commonly experience urinary tract infection (UTI) recurrence. However, there is no effective tool for predicting recurrent UTI after the first UTI episode. Hence, this study aimed to investigate potential urinary inflammatory biomarkers and specific biomarkers for predicting UTI recurrence or persistence after antibiotic treatment in women.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!