The study objective is to develop an epidemiological model of brucellosis transmission dynamics among cattle in India and to estimate the impact of different prevention and control strategies. The prevention and control strategies are test-and-slaughter, transmission rate reduction, and mass vaccination. We developed a mathematical model based on the susceptible-infectious-recovered epidemic model to simulate brucellosis transmission dynamics, calibrated to the endemically stable levels of bovine brucellosis prevalence of cattle in India. We analyzed the epidemiological benefit of different rates of reduced transmission and vaccination. Test-and-slaughter is an effective strategy for elimination and eradication of brucellosis, but socio-cultural constraints forbid culling of cattle in India. Reducing transmission rates lowered the endemically stable levels of brucellosis prevalence correspondingly. One-time vaccination lowered prevalence initially but increased with influx of new susceptible births. While this epidemiological model is a basic representation of brucellosis transmission dynamics in India and constrained by limitations in surveillance data, this study illustrates the comparative epidemiological impact of different bovine brucellosis prevention and control strategies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537291 | PMC |
| http://dx.doi.org/10.1109/BigData.2014.7004420 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bovine brucellosis, associated risk factors and preventive measures in industrial cattle farms.
Heliyon
November 2024
Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Effective management of brucellosis in human populations is closely tied to controlling the disease in domestic livestock. This study focused on identifying determinants of brucellosis prevalence in mixed industrial dairy and beef cattle farms within Isfahan Province, Iran. Employing a case control design, we compared 32 ranches with documented brucellosis within the previous year (12 months) to 38 farms with no brucellosis during the same timeframe.
View Article and Find Full Text PDFSensitivity analysis and dynamics of brucellosis infection disease in cattle with control incident rate by using fractional derivative.
Sci Rep
January 2025
Faculty of Informatics and Computing, Universiti Sultan Zainal Abidin, Campus Besut, 22200, Terengganu, Malaysia.
The farming of animals is one of the largest industries, with animal food products, milk, and dairy being crucial components of the global economy. However, zoonotic bacterial diseases, including brucellosis, pose significant risks to human health. The goal of this research is to develop a mathematical model to understand the spread of brucellosis in cattle populations, utilizing the Caputo-Fabrizio operator to control the disease's incidence rate.
View Article and Find Full Text PDFA knowledge, attitude and practices assessment of control measures for bovine tuberculosis and brucellosis towards a more effective approach to national control programs in South Africa.
Trop Anim Health Prod
January 2025
Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, Onderstepoort, University of Pretoria, Pretoria, South Africa.
Bovine brucellosis and bovine tuberculosis are zoonotic diseases with economic and public health importance across the world, especially in developing countries where the diseases are endemic. The diseases are classified as neglected diseases in developing nations with poor resources despite good control measures in some developed countries. The purpose of this study is to assess the knowledge, attitudes and perceptions (KAP) of stakeholders towards control measures for bovine brucellosis (BR) and bovine tuberculosis (bTB) at a livestock-wildlife interface.
View Article and Find Full Text PDFSystematic review on the effectiveness of Brucella abortus S19 and RB51 vaccine strains in field studies.
Vaccine
January 2025
Departamento de Medicina Veterinária, Faculdade de Zootecnia e Medicina Veterinária, Universidade Federal de Lavras - UFLA, Lavras, Minas Gerais, Brazil. Electronic address:
Brucella abortus S19 and RB51 are the most used vaccines to control bovine brucellosis worldwide; therefore, this study aimed to perform a systematic review on the effectiveness of these two vaccine strains in field studies. The literature review was conducted on April 3rd 2020 on six databases (CABI, Cochrane, PubMed, Scielo, Scopus and Web of Science) and included papers published between 1976 and 2016. The search strategy recovered a total of 5846 papers on databases and 6 papers were included due to specialists' suggestions.
View Article and Find Full Text PDFPrevalence and herd-level risk factors associated with Brucella infection in smallholders keeping large ruminants.
Res Vet Sci
February 2025
Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong SAR, China; UKMC, Manchester M11 1AA, UK. Electronic address:
Brucellosis is a disease that poses a higher risk of transmission to animals and people who have close interactions with them, such as farmers. Therefore, the present study was designed to determine the seroprevalence of bovine brucellosis and associated risk factors in Kasur, Punjab, Pakistan. One hundred pooled milk samples from 100 smallholder mixed herds of cows and buffaloes with a total study population of 425 animals (277 cattle and 148 buffalos) with a range of up to seven animals in each herd were collected and tested through a milk ring test (MRT).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!