Liver transplantation procedures are being performed at an increasing number of hospitals throughout the United States. These procedures are challenging because of hemodynamic, metabolic, renal, and coagulation dysfunctions and may require prolonged periods of time for completion. Anesthesia departments are developing or managing teams of personnel to perform liver transplants. A survey was sent to directors of liver transplant anesthesia teams to investigate how teams were structured, compensated, and the impact of participation upon personnel involved. Thirty-nine centers were surveyed and 31 responded. The results showed an arithmetic doubling of cases for each of the last six years, most being performed at large medical centers (more than 759 beds) with populations served of 2 million or more. Cases were reported to average 13 hours in length and required a mean of five anesthesia personnel to complete. Compensation methods for work on a liver transplant team were variable; however, CRNAs and technicians received monetary reimbursement more frequently than physicians. Emotional responses of personnel were equally divided between favorable and unfavorable responses. Discriminate analysis showed that positive personnel attitudes were most closely tied to the presence of a protocol for breaks, call schedules, compensation, and the frequency of performing these cases. However, most protocols for personnel management were instituted in response to dissatisfaction. As the number of transplants per year increases, departments will need effective plans for personnel management to maximize departmental resources, increase research interest, and maintain personnel enthusiasm.
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http://dx.doi.org/10.1016/0952-8180(89)90040-8 | DOI Listing |
Am J Physiol Gastrointest Liver Physiol
January 2025
Metabolism and Nutrition Department. NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa. Lisbon, Portugal.
Appetite, as the internal drive for food intake, is often dysregulated in a broad spectrum of conditions associated with over- and under-nutrition across the lifespan. Appetite regulation is a complex, integrative process comprising psychological and behavioral events, peripheral and metabolic inputs, and central neurotransmitter and metabolic interactions. The microbiota-gut-brain axis has emerged as a critical mediator of multiple physiological processes, including energy metabolism, brain function, and behavior.
View Article and Find Full Text PDFHepatic ischemia-reperfusion injury (IRI) poses a significant threat to clinical outcomes and graft survival during hemorrhagic shock, hepatic resection, and liver transplantation. Current pharmacological interventions for hepatic IRI are inadequate. In this study, we identified ginsenoside Rk2 (Rk2), a rare dehydroprotopanaxadiol saponin, as a promising agent against hepatic IRI through high-throughput screening.
View Article and Find Full Text PDFGastro Hep Adv
September 2024
Division of Gastroenterology and Hepatology, Duke University, Durham, North Carolina.
Background And Aims: Alcohol-related liver disease is a leading cause of liver transplantation (LT) in the United States; however, alcohol relapse remains a risk, and real-world assessment of relapse prediction scores is lacking. The primary aim of this study was to assess risk factors for alcohol relapse and compare effectiveness of pre-existing risk scores (e.g.
View Article and Find Full Text PDFWorld J Gastroenterol
January 2025
Senior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing 100071, China.
In this article, we comment on an article published in a recent issue of the . We specifically focus on the roles of human leukocyte antigen (HLA) and donor-specific antibodies (DSAs) in pediatric liver transplantation (LT), as well as the relationship between immune rejection after LT and DSA. Currently, LT remains the standard of care for pediatric patients with end-stage liver disease or severe acute liver failure.
View Article and Find Full Text PDFLancet Reg Health Eur
February 2025
University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
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