Despite decrease in morbidity and mortality from invasive pneumococcal disease (IPD), individuals with asplenia remain at risk for IPD compared to the general population. This report describes a young adult with hemoglobin SD and documented splenic autoinfarction with pneumococcal sepsis, meningitis, and pneumonia within seven months of immunization with PPSV-23.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527808PMC
http://dx.doi.org/10.1002/ccr3.276DOI Listing

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