Objectives/hypothesis: To describe anatomical landmarks for endoscopic endonasal approaches to the orbital apex and to measure the distances between those landmarks.
Methods: In this anatomic study, the nasal fossae of 30 adult fresh cadavers were dissected (n = 60 half-skulls). One double-injected orbit was carefully dissected, mainly focusing on the neurovascular structures. The orbital apex was dissected under endoscopic endonasal visualization in all cases. The distances between the ethmoidal crest and choanal arch to the optic canal (OC) and superior orbital fissure (SOF) were measured and recorded.
Results: The sample was predominantly male (63.3%, 19/30 cadavers). The following correlations between measurements according to side were observed: ethmoidal crest to OC, r = 0.748 (P = 0.0001); ethmoidal crest to SOF, r = 0.785 (P = 0.0001); choanal arch to OC, r = 0.835 (P = 0.0001); choanal arch to SOF, r = 0.820 (P = 0.0001).
Conclusions: In the cadavers studied in this sample, the ethmoidal crest and choanal arch were relevant structures and exhibited consistent measurements. Spearman correlation coefficients were greater than 0.7, which is indicative of good correlation between measurements obtained in the skull halves of each cadaver. Comparison of the measurements obtained in different sides showed similar values, with no statistically significant differences in the distances between any of the proposed anatomic landmarks.
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http://dx.doi.org/10.1002/lary.25327 | DOI Listing |
Anat Cell Biol
December 2024
Department of Neurosurgery, Tulane Center for Clinical Neurosciences, Tulane University School of Medicine, New Orleans, LA, USA.
The ethmoidal foramina (EF), located on the medial orbital wall along the frontoethmoidal sutures, are critical anatomical landmarks for surgeries involving the medial orbital wall. This review aimed to review the surgical anatomy of the EF, including their embryology and radiology. Although the frontoethmoidal sutures mostly have two foramina passing through them, there are reports of single foramen or multiple, up to six foramina.
View Article and Find Full Text PDFCureus
September 2024
Otolaryngology - Head and Neck Surgery, King Abdulaziz Medical City Riyadh, Riyadh, SAU.
The nasal septum consists of the quadrangular septal cartilage, the maxillary and palatine bone crests, the perpendicular plate of the ethmoid bone, and the vomer. Congenital agenesis of the vomer is a rare condition. This case involves a 29-year-old male who presented to our clinic with alternating bilateral nasal obstruction and no history of allergic symptoms.
View Article and Find Full Text PDFDev Dyn
September 2024
Department of Orthodontics and Dentofacial Orthopedics, Osaka University Graduate School of Dentistry, Suita, Japan.
Background: Embryonic craniofacial development involves several cellular and molecular events that are evolutionarily conserved among vertebrates. Vertebrate models such as mice and zebrafish have been used to investigate the molecular and cellular etiologies underlying human craniofacial disorders, including orofacial clefts. However, the molecular mechanisms underlying embryonic development in these two species are unknown.
View Article and Find Full Text PDFClin Anat
January 2025
Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Endoscopic endonasal skull base surgery is increasingly prevalent, with its scope expanding from pathogens in the midline region to those in the paramedian region. Maximizing anterior sphenoidectomy is important for the median approach, and lateralizing the pterygopalatine fossa is crucial for the paramedian approach. Maximizing the surgical corridor in the nasal cavity and minimizing damage to neurovascular structures are vital for establishing a surgical field with minimal bleeding, ensuring safe, precise, and gentle procedures.
View Article and Find Full Text PDFInt J Biol Macromol
May 2024
Laboratory of Developmental Disorders and Toxicology, Center for Promotion of International Education and Research, Faculty of Agriculture, Kyushu University, Fukuoka 819-0395, Japan. Electronic address:
Treacher Collins syndrome-3 (TCS-3) is a rare congenital craniofacial disorder attributed to variants in the RNA pol I subunit C (POLR1C). The pathogenesis of TCS-3 linked to polr1c involves the activation of apoptosis-dependent p53 pathways within neural crest cells (NCCs). This occurs due to disruptions in ribosome biogenesis, and the restoration of polr1c expression in early embryogenesis effectively rescues the observed craniofacial phenotype in polr1c-deficient zebrafish.
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