Right-to-left shunt (RLS) is associated with cryptogenic stroke and migraine. Herein we investigated the relationship between RLS and silent lacunar infarcts in patients with migraine. A total of 263 patients with migraine who met eligibility criteria were enrolled from January 2010 to December 2011, among which 127 subjects fell into RLS group. Baseline demographics were comparable between RLS and non-RLS groups (P > 0.05). The incidence of silent lacunar infarcts in RLS group was not significantly different from that of the non-RLS group (25.2% versus 21.3%, P > 0.05). Furthermore, we found that the incidence of silent lacunar infarcts in permanent and latent RLS subgroups was comparable with non-shunt RLS subgroup (28.6% versus 24% versus 21.3%, P > 0.05). Similarly, the incidence of silent lacunar infarcts in the non-RLS group, mild-shunt group, and large-shunt group was also comparable (21.3% versus 23.8% versus 29.3%, P > 0.05). In addition, RLS did not increase the incidence of silent lacunar infarcts in migraine patients with elder age (< 50 years age group: 15.8% versus 17.9%; ≥ 50 years age group: 53.1% versus 37.5%, both P > 0.05). In conclusion, RLS does not increase the incidence of silent lacunar infarcts in patients with migraine. Further prospective studies are warranted to validate this finding.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523651 | PMC |
| http://dx.doi.org/10.1155/2015/749745 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparison of Asymptomatic Brain Lesions Between Thalassemia Major and Sickle Cell Anemia Patients.
Medicina (Kaunas)
January 2025
Department of Thalassemia Unit, Hatay Education and Research Hospital, Hatay 31027, Turkey.
This study aimed to identify asymptomatic brain lesions in patients with β-thalassemia major (TM) and sickle cell anemia (SCA) and evaluate the correlation of these lesions with factors such as splenectomy, thrombocytosis, and blood transfusions. A total of 26 patients with thalassemia major and 23 patients with sickle cell anemia were included. Ischemic lesions were categorized as lacunar, small vessel, or multifocal.
View Article and Find Full Text PDFThe added value of b0-DWI analysis in the diagnosis of cavitating lacunes when T2-weighted spin-echo is unavailable.
Eur J Radiol
January 2025
Regional University Hospital Centre of Orléans, Diagnostic Neuroradiology Department, France. Electronic address:
Purpose: Silent brain infarcts, sometimes appearing as incidental lacunes in patients with unknown history of vascular event, are linked to dementia, gait disturbances and depression. We observed that some cavitating lacunes were only visible on b0-diffusion-weighted-imaging (b0-DWI: T2-weighted without diffusion gradients) when T2-weighted-spin-echo (T2-SE) was unavailable. We aimed to evaluate the additional value of b0-DWI in detecting cavitating lacunes.
View Article and Find Full Text PDFSilent brain infarctions in patients with rheumatic mitral stenosis.
Clin Neurol Neurosurg
December 2024
Neurology department (I.N, M.F.B), Hassan II University Hospital, Fez, Morocco; Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdallah University, Fez, Morocco.
Background: Silent brain infarctions (SBI) are commonly detected in brain imaging. The association of SBI with rheumatic mitral stenosis (MS) is not clearly relevant. Based on magnetic resonance imaging, we aimed to describe the prevalence of SBI in patients with rheumatic MS and the cardiac abnormalities related to their occurrence.
View Article and Find Full Text PDFCorrelation of silent brain infarcts and leukoaraiosis in middle-aged ischemic stroke patients: a retrospective study.
Front Neurol
August 2024
Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Article Synopsis
- - The study investigates the link between silent brain infarcts (SBI) and leukoaraiosis in middle-aged ischemic stroke patients, finding a significant association between the two conditions in a sample of 50 individuals.
- - Out of the participants, 52% showed signs of leukoaraiosis, with over 65% of those also having SBI, and a high prevalence of metabolic syndrome (MetS) was noted among the group.
- - The research emphasizes that leukoaraiosis is a critical risk factor for SBI, indicating that enhanced imaging methods can help in diagnosing cerebrovascular conditions related to age and hypertension, though further studies are needed for improved understanding and treatment.
Cerebrovascular Involvement in Transthyretin Amyloid Cardiomyopathy.
J Clin Med
July 2024
Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, 1090 Vienna, Austria.
Article Synopsis
- Intracardiac thrombosis is frequent in patients with transthyretin amyloid cardiomyopathy (ATTR-CM), leading to potential risks like thromboembolic events, but the impact on brain health remains unclear.
- A study involving 32 ATTR-CM patients showed significant findings using cerebral magnetic resonance imaging (cMRI), indicating they had more territorial infarcts, microbleeds, and Virchow-Robin spaces compared to matched controls.
- The results suggest that even asymptomatic ATTR-CM patients might benefit from routine cMRI screening and consideration for anticoagulation therapy due to underlying cerebral vessel disease.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!