Necrotizing fasciitis (NF) is an aggressive and life-threatening infection of skin and soft tissue characterized by widespread fascial necrosis, leads to gross morbidity and mortality if left untreated. Although MRSA has become a common isolate associated with skin and soft tissue infections globally over the past few years, monomicrobial MRSA NF has been reported only in a few studies. Our case represents the development of NF followed by trivial trauma salvaged with daptomycin and amputation of the affected limb. Prompt diagnosis and surgical management with empiric MRSA cover in areas where community acquired MRSA (CA-MRSA) is endemic for suspected cases of necrotizing fasciitis can prevent the dreaded consequences.
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http://dx.doi.org/10.7860/JCDR/2015/12381.6014 | DOI Listing |
Microorganisms
January 2025
Emergency, Anesthesiological and Reanimation Sciences Department, Fondazione Policlinico Universitario A. Gemelli-IRCCS of Rome, 00168 Rome, Italy.
() is a Gram-negative, halophilic bacillus known for causing severe infections such as gastroenteritis, necrotizing fasciitis, and septic shock, with mortality rates exceeding 50% in high-risk individuals. Transmission occurs primarily through the consumption of contaminated seafood, exposure of open wounds to infected water, or, in rare cases, insect bites. The bacterium thrives in warm, brackish waters with high salinity levels, and its prevalence is rising due to the effects of climate change, including warming ocean temperatures and expanding coastal habitats.
View Article and Find Full Text PDFActa Ortop Mex
January 2025
Department of Orthopedic and Trauma Surgery, Hospital Quironsalud Badalona. Barcelona, Spain.
Introduction: necrotizing fasciitis (NF) is a rare soft tissue infection that leads to sepsis and death without an early surgical treatment. LRINEC (laboratory risk indicator for necrotizing fasciitis) scale is one of the most accepted tests for diagnosis. This study presents a retrospective evaluation of the usefulness of the LRINEC scale in the diagnosis and prognosis of NF.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Surgery, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka. Electronic address:
Introduction: Necrotizing fasciitis (NF) is a rapidly progressive life-threatening infection involving necrosis of subcutaneous tissues and fascia. Though it mainly affects the extremities, perineum and abdominal wall, it rarely affects the breast.
Presentation Of Case: A 30-year-old woman on postpartum day seven presented with one-day history of fever with chills and rigors and painful, swollen and tender left breast.
Front Med (Lausanne)
January 2025
Department of Emergency Medicine, The First People's Hospital of Kunshan, Kunshan, China.
Background: A liver abscess caused by hypervirulent can lead to multiple invasive extrahepatic infections, including lung abscesses, endophthalmitis, brain abscesses, and necrotizing fasciitis. This condition, known as liver abscess invasion syndrome, progresses rapidly and is associated with severe illness, high disability rates, and significant mortality. However, bloodstream infections with co-infection involving carbapenem-resistant are exceedingly rare.
View Article and Find Full Text PDFSurg Pract Sci
December 2024
Department of Gastrointestinal and Anal Diseases, Shenyang Coloproctology Hospital, Shenyang, PR China.
Background: Fournier's gangrene (FG) is scarce and potentially fatal disease. Although the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score was established in 2004, its reliability as a diagnostic tool to differentiate between FG and perianal abscess is still debated. The objective of this study was to assess the reliability of the LRINEC score and other relevant inflammatory markers.
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