Three New Isomeric Indole Alkaloids from Nauclea officinalis.

Chem Biodivers

Key Laboratory of Rare and Uncommon Diseases, Institute of Materia Medica, Shandong Academy of Medical Sciences, Ji'nan, 250062, Shandong, P. R. China, (phone: +86-531-82919963; fax: +86-531-82919963).

Published: August 2015

Three new isomeric monoterpene indole alkaloids, naucleofficines I-III (1-3, resp.) were isolated from the stems (with bark) of Nauclea officinalis. Their structures were elucidated on the basis of spectroscopic methods and single-crystal diffraction analyses. The cytotoxic activities of 1-3 against human colon cancer, human gastric cancer, and human hepatoma cells were also investigated.

Download full-text PDF

Source
http://dx.doi.org/10.1002/cbdv.201400289DOI Listing

Publication Analysis

Top Keywords

three isomeric
8
indole alkaloids
8
nauclea officinalis
8
cancer human
8
isomeric indole
4
alkaloids nauclea
4
officinalis three
4
isomeric monoterpene
4
monoterpene indole
4
alkaloids naucleofficines
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!