AI Article Synopsis
- Buerger's disease, also known as thromboangiitis obliterans, leads to pain and may result in ulceration or gangrene in limbs, primarily linked to chronic cigarette smoking.
- The exact cause of this immune-mediated vasculitis remains unclear, but recent theories suggest a connection with certain bacteria found in dental infections.
- Treatment options have been limited, and the most effective approach currently is to stop smoking.
Article Abstract
Buerger's disease or thromboangiitis obliterans causes pain, ulceration, or gangrene in the lower or upper extremity. It is associated with chronic cigarette smoking and is believed to be an immune mediated vasculitis. The pathogenesis is still unknown but recent postulate of its association with odontal bacteria has generated much renewed interest. Despite its recognition more than a century ago, little progress has been made in its treatment. Until the pathogenesis is elucidated, abstinence from cigarette is the only effective therapy.
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| http://dx.doi.org/10.1177/1534734615599654 | DOI Listing |
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