AI Article Synopsis
- Hepatic lipid peroxidation increased in cholestatic rats alongside elevated hydroxyproline levels.
- Feeding cholestatic rats a copper-supplemented diet resulted in a significant increase in liver copper levels (about 16-fold).
- Despite the rise in copper, there were no changes in hepatic lipid peroxidation or hydroxyproline levels in the copper-supplemented group compared to normally fed cholestatic rats.
Article Abstract
Hepatic lipid peroxidation was shown to be stimulated in the livers of cholestatic rats with increased hydroxyproline levels. In another group, cholestatic rats were fed with a copper-supplemented diet to increase hepatic copper levels. Although liver copper concentrations increased about 16-fold in copper supplemented cholestatic rats compared to normally fed cholestatic rats, no change was observed either in hepatic lipid peroxidation or in hydroxyproline levels.
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| http://dx.doi.org/10.1016/1043-6618(89)90229-6 | DOI Listing |
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