Implementation of mild therapeutic hypothermia after cardiac arrest into clinical practice is a continuing process. Although ILCOR recommendation was given in 2003, only 24% of the German hospitals reported the use of hypothermia in this setting in 2005. Growing evidence and most importantly the implementation of hypothermia into the guidelines led to a significant increase of acceptance of this therapeutic option leading to a user rate of 69% in 2009. Encouraged by the new guidelines from 2010 86% of German hospitals finally reported to use hypothermia after cardiac arrest routinely in 2012, a decade after publication of the mile stone studies. The phenomenon of a delayed implementation of hypothermia into clinical practice can be seen throughout the world as many surveys from different countries at different time points have shown. When hypothermia is used, hospitals go with the guidelines quite strictly with respect to indication, duration of treatment and target temperature. This strengthens the importance of guidelines in the process to implement new therapeutic options. However, although a recent study still promotes a strict target temperature management it questions the need for a markedly reduced target temperature of 33°C. It remains to be elucidated how this study will affect the daily routine in the hospitals and most interestingly how this study will change the coming guidelines in 2015.

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0041-103570DOI Listing

Publication Analysis

Top Keywords

target temperature
12
therapeutic hypothermia
8
hypothermia clinical
8
hypothermia cardiac
8
cardiac arrest
8
clinical practice
8
german hospitals
8
reported hypothermia
8
implementation hypothermia
8
study will
8

Similar Publications

The Anoplophora chinensis (Coleoptera: Cerambycidae) (Forster), a serious phytophagous pest threatening Castanea mollissima Blume and Castanea seguinii Dode, poses risks of ecological imbalance, significant economic loss, and increased management difficulties if not properly controlled. This study employs optimized MaxEnt models to analyze the potential distribution areas of A. chinensis and its host plants under current and future climate conditions, identifying their movement pathways and relative dynamics.

View Article and Find Full Text PDF

Pleurotus ostreatus is a nutrient-dense edible fungus renowned for its delicate texture, appealing flavor, and numerous potential health benefits. Simultaneous extraction within the framework of food resource processing facilitates the concurrent isolation and analysis of multiple target compounds. In this study, an ethanol/salt aqueous two-phase system (ATPS) was employed to extract polysaccharides (PS) and proteins from P.

View Article and Find Full Text PDF

Exploring drought dynamics has become urgent due to unprecedented climate change. Projections indicate that drought events will become increasingly widespread globally, posing a significant threat to the sustainability of the agricultural sector. This growing challenge has resulted in heightened interest in understanding drought dynamics and their impacts on agriculture.

View Article and Find Full Text PDF

Thiamin, an essential micronutrient, is a cofactor for enzymes involved in the central carbon metabolism and amino acids pathways. Despite efforts to enhance thiamin content in rice by incorporating thiamin biosynthetic genes, increasing thiamin content in endosperm remains challenging, possibly due to a lack of thiamin stability and/or a local sink. The introduction of storage proteins has been successful in biofortification strategies and similar efforts targeting thiamin led to a 3-4-fold increase in white rice.

View Article and Find Full Text PDF

Semiconductor metal oxide (SMO) gas sensors are gaining prominence owing to their high sensitivity, rapid response, and cost-effectiveness. These sensors detect changes in resistance resulting from oxidation-reduction reactions with target gases, responding to a variety of gases simultaneously. However, their inherent limitations lie in selectivity.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!