In this study, we describe the molecular characterization of a plasmid-located blaNDM-1 harbored by an Acinetobacter clinical isolate recovered from a patient in Turkey that putatively constitutes a novel Acinetobacter species, as shown by its distinct ARDRA (amplified 16S ribosomal DNA restriction analysis) profile and molecular sequencing techniques. blaNDM-1 was carried by a conjugative plasmid widespread among non-baumannii Acinetobacter isolates, suggesting its potential for dissemination before reaching more clinically relevant Acinetobacter species.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576105 | PMC |
| http://dx.doi.org/10.1128/AAC.01455-15 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii.
Biol Res
January 2025
Department of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166, Rome, Italy.
Background: Acinetobacter baumannii poses a significant threat globally, causing infections primarily in healthcare settings, with high mortality rates. Its adaptability to antibiotic resistance and tolerance to various stresses, including reactive oxygen species (ROS), contribute to its persistence in healthcare environments. Previous evidence suggested that the periplasmic heat shock protein, HslJ-like protein (ABUW_2868), could be involved in oxidative stress defense in A.
View Article and Find Full Text PDFIn silico characterization of defense system hotspots in Acinetobacter spp.
Commun Biol
January 2025
Bioinformatics Laboratory, Infectious Diseases and Pathogen Biology Center, The First Hospital of Jilin University, Changchun, China.
The bacteria-phage arm race drives the evolution of diverse bacterial defenses. This study identifies and characterizes the defense hotspots in Acinetobacter baumannii using a reference-free approach. Among 4383 high-quality genomes, we found a total of 17,430 phage defense systems and with 54.
View Article and Find Full Text PDFCo-occurrence of microplastics, PFASs, antibiotics, and antibiotic resistance genes in groundwater and their composite impacts on indigenous microbial communities: A field study.
Sci Total Environ
January 2025
State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 211135, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
There is a major gap in the occurrence of mixed emerging contaminants, which hinders our efforts in exploring their behaviors and transport in environmental media, as well as their toxicity to human and ecosystem. This study assessed the occurrence and their correlations of mixed contamination by microplastics (MPs), per- and polyfluoroalkyl substances (PFASs), antibiotics, and antibiotic resistance genes (ARGs) in groundwater collected from a pharmaceutical and chemical industrial park. MPs, PFASs, antibiotics and ARGs were detected at all monitoring wells.
View Article and Find Full Text PDFEvaluating the potential of in alleviation of aluminium stress in .
3 Biotech
January 2025
Department of Agronomy, Abdul Wali Khan University, Mardan, 23200 Khyber Pakhtunkhwa Pakistan.
Soil contamination with toxic heavy metals [such as aluminum (Al)] is becoming a serious global problem due to the rapid development of the social economy. Although plant growth-promoting rhizo-bacteria (PGPR) are the major protectants to alleviate metal toxicity, the study of these bacteria to ameliorate the toxic effects of Al is limited. Therefore, the present study was conducted to investigate the combined effects of different levels of (5 ppm and 10 ppm) of accession number of MT123456 on plant growth and biomass, photosynthetic pigments, gas exchange attributes, oxidative stress and response of antioxidant compounds (enzymatic and nonenzymatic), and their specific gene expression, sugars, nutritional status of the plant, organic acid exudation pattern and Al accumulation from the different parts of the plants, which was spiked with different levels of Al [0 µM (i.
View Article and Find Full Text PDFReconsidering the Diagnosis: Abnormal Sweat Chloride Tests in Non-CF Bronchiectasis.
Pediatr Pulmonol
January 2025
Department of Internal Medicine, Division of Pulmonary and Critical Care, University of Virginia, Charlottesville, Virginia, USA.
Introduction: While the diagnosis of cystic fibrosis (CF) is often straightforward and reliant on correlation between genetic testing and clinical signs and symptoms, there is a subset where the distinction is not nearly as clearcut. This has previously been reported in patients identified through newborn screening but not meeting full CF diagnostic criteria, earning the label of CF Screen Positive, Inconclusive Diagnosis (CFSPID) instead. A homologous diagnostic category in adults is named CF Transmembrane Conductance Regulator-Related Disorder (CFTR-RD).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!