Objective: Research shows that mindfulness meditation (MM) affects pain perception; however, studies have yet to measure patterns of change over time. We examined effects of MM on perception of experimental heat pain using multiple psychophysical indices, including pattern of change in response to tonic painful stimuli. We also tested the potential moderating role of baseline mindfulness.
Method: Forty participants were randomly assigned to a brief MM training or control group. We assessed: a) heat pain threshold (HPT), b) temperature which induces pain at a fixed, target intensity level, and c) response pattern over time to tonic heat pain.
Results: Compared to control group, the MM group showed increased HPT and more rapid attenuation of pain intensity for tonic pain stimuli. Moderation analyses indicated that baseline mindfulness moderated effects of MM on HPT.
Conclusions: A brief MM intervention appears to affect perception of experimental pain both by increasing pain threshold and accelerating modulation of response. Findings may help elucidate mechanisms of MM for chronic pain.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/pme.12883 | DOI Listing |
J Pain Res
January 2025
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Purpose: Spinal cord stimulation (SCS) is pivotal in treating chronic intractable pain. To elucidate the mechanism of action among conventional and current novel types of SCSs, a stable and reliable electrophysiology model in the consensus animals to mimic human SCS treatment is essential. We have recently developed a new in vivo implantable pulsed-ultrahigh-frequency (pUHF) SCS platform for conducting behavioral and electrophysiological studies in rats.
View Article and Find Full Text PDFBMC Med Res Methodol
January 2025
Faculty of Social Sciences (Health Sciences) and Gerontology Research Center (GEREC), Tampere Universities, Tampere, Finland.
Background And Method: This study set out to identify the factors and combinations of factors associated with the individual's premature death, using data from the Finnish Longitudinal Study on Ageing Municipal Employees (FLAME) which involved 6,257 participants over a 29-year follow-up period. Exact dates of death were obtained from the Finnish population register. Premature death was defined as a death occurring earlier than the age- and sex-specific actuarial life expectancy indicated by life tables for 1981, as the baseline, with the threshold period of nine months.
View Article and Find Full Text PDFBrain Res Bull
January 2025
Department of Pharmacology, Shaanxi University of Chinese Medicine, Xianyang, 712046, PR China; Key Laboratory of Pharmacodynamic Mechanism and Material Basis of Traditional Chinese Medicine, Shaanxi Administration of Traditional Chinese Medicine, Xianyang 712046, PR China. Electronic address:
Diabetic neuropathic pain (DNP) is a common complication of diabetes mellitus (DM) and is characterized by spontaneous pain and neuroinflammation. The Sigma-1 receptor (Sig-1R) has been proposed as a target for analgesic development. It is an important receptor with anti-inflammatory properties and has been found to regulate DNP.
View Article and Find Full Text PDFJ Dent
January 2025
Department of Oral & Maxillofacial Radiology, Peking University School & Hospital of Stomatology, Beijing 100081, China; National Center for Stomatology & National Clinical Research Center for Oral Diseases, Beijing 100081, China; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China; Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China. Electronic address:
Objectives: In this study, artificial intelligence techniques were used to achieve automated diagnosis and classification of temporomandibular joint (TMJ) degenerative joint disease (DJD) on cone beam computed tomography (CBCT) images.
Methods: An AI model utilizing the YOLOv10 algorithm was trained, validated and tested on 7357 annotated and corrected oblique sagittal TMJ images (3010 images of normal condyles and 4347 images of condyles with DJD) from 1018 patients who visited Peking University School and Hospital of Stomatology for temporomandibular disorders and underwent TMJ CBCT examinations. This model could identify DJD as well as the radiographic signs of DJD, namely, erosion, osteophytes, sclerosis and subchondral cysts.
PLoS One
January 2025
Department of Anorectal Surgery, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Background And Purpose: Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are widely performed surgeries for end-stage joint disease, yet the influence of depression and anxiety on postoperative outcomes remains unclear. This study aims to consolidate current evidence on the relationship between preoperative depression and/or anxiety disorders and postoperative outcomes in adult patients undergoing primary THA or TKA. Given the potential for these psychiatric conditions to affect recovery, pain management, and overall satisfaction, the results of this study are crucial to inform targeted perioperative interventions and improve patient-centered care.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!