Transplant recipients are at risk of developing Legionnaires' disease (LD) because of impaired cellular immunity. Here, we describe a renal transplant recipient who developed LD at least 10 days after hospital admission and transplantation. The hospital water network was initially suspected, but further testing determined that the probable source was the patient's domestic water supply. Our report also suggests that the patient's immunosuppressed state may have switched potential colonization to pneumonia.

Download full-text PDF

Source
http://dx.doi.org/10.1111/tid.12432DOI Listing

Publication Analysis

Top Keywords

legionnaires' disease
8
renal transplant
8
transplant recipient
8
community-acquired legionnaires'
4
disease renal
4
recipient unclear
4
unclear incubation
4
incubation period
4
period molecular
4
molecular typing
4

Similar Publications

subverts the antioxidant defenses of its amoeba host .

Curr Res Microb Sci

January 2025

Université de Poitiers, UMR CNRS 7267, Ecologie et Biologie des Interactions, France.

, the causative agent of Legionnaires' disease, interacts in the environment with free-living amoebae that serve as replicative niches for the bacteria. Among these amoebae, is a natural host in water networks and a model commonly used to study the interaction between and its host. However, certain crucial aspects of this interaction remain unclear.

View Article and Find Full Text PDF

Sprinkler irrigation of urban sport fields as a potential source of .

Arch Environ Occup Health

January 2025

Environmental Quality and Intervention Department, Agència de Salut Pública de Barcelona, Barcelona, Spain.

Following a legionnaire's disease outbreak in Barcelona in 2022, sport fields' sprinklers were identified as potential sources of Legionella infection. The Agency of Public Health of Barcelona inspected all 40 urban municipal sports fields in the city. was found in 55% of them, including in 11 samples.

View Article and Find Full Text PDF

and are two phylogenetically related bacterial pathogens that exhibit extreme intrinsic resistance when they enter into a dormancy-like state. This enables both pathogens to survive extended periods in growth-limited environments. Survival is dependent upon their ability to undergo developmental transitions into two phenotypically distinct variants, one specialized for intracellular replication and another for prolonged survival in the environment and host.

View Article and Find Full Text PDF

Occurrence of macrolides resistance in Legionella pneumophila ST188: results of the Belgian epidemiology and resistome investigation of clinical isolates.

Int J Infect Dis

January 2025

National reference centre for Legionella pneumophila, Department of Microbiology, Universitair Ziekenhuis Brussel (UZ Brussel), Vrije Universiteit Brussel (VUB), Laarbeeklaan 101, 1090 Brussels, Belgium.

Introduction: The incidence of Legionnaires' disease (LD) steadily increases worldwide. Although Legionella pneumophila is known as pathogenic, systematic investigations into antibiotic resistance are scarce, and reports of resistance in isolates are recently emerging.

Methods: Clinical cases and metadata reported to the Belgian National Reference Centre between 2011 and 2022 were retrospectively analysed.

View Article and Find Full Text PDF

Background: Legionella pneumophila is an uncommon pathogen causing community-acquired atypical pneumonia. Acinetobacter baumannii is a major pathogen responsible for hospital-acquired pneumonia, but it rarely causes serious infections in a community setting. Without prompt and appropriate treatments, infection from either of these two pathogens can cause a high mortality rate.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!