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Background: Medical education in North America was shaped by a biomedically bounded framework dating back to the early nineteenth century. Yet, one renowned physician, William Osler (1849-1919), seemed to stand out among his contemporaries by promoting acupuncture as a form of treatment. Some physicians in the early 1970s proposed that Osler was ahead of his time by including acupuncture in his medical textbook, (1892).

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Background And Aims: The presence of sections or chapters on spontaneous human combustion in more than half of the key texts in English on the action of alcohol on the body and mind in the first half of the nineteenth century demonstrates the seriousness with which it was considered. We aimed to chart discussions about the links between spontaneous human combustion and spirit drinking in medical texts and representations in fiction through three key chronological periods from 1804 to 1900.

Methods: A contextual analysis using eighteenth- and nineteenth-century historical, literary and medical sources to chart and reflect on public and medical discourses.

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Sample preparation is the process of altering a naturally occurring object into a representative form that is amenable to scientific inquiry. Preparation is an important preliminary to data collection, ubiquitous in the life sciences and elsewhere, yet relatively neglected in historical and philosophical literature. This paper presents a detailed historical case study involving the preparation and study of blood crystals in the nineteenth century.

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Guinea worm is a debilitating waterborne parasitic disease with a long history. This paper examines the ways guinea worm was understood in English-language scientific literature between 1688 and 1931. In the early eighteenth century, guinea worm was principally understood by English-speaking physicians as an exotic wonder of faraway lands.

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Edward Reynolds Hun is easily eclipsed by his father, Thomas (1808-1896), and his younger brother, Henry (1854-1924), in historical accounts of the evolution of neurology as a clinical specialty and academic discipline in nineteenth-century America. His early educational pathway, including a postgraduate year in Paris, was typical for sons of the wealthy seeking a medical degree. On his return from Europe, he embarked on a research career in neuropsychiatry seeking to uncover biochemical and pathological underpinnings for psychiatric disorders.

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