AI Article Synopsis

  • The study aimed to determine how common pseudotumors are in patients with metal-on-metal hip replacements, analyze their characteristics using MARS-MRI, and examine the link between pseudotumors and metal ions.
  • The research involved a review of 102 patients, revealing that 68.6% had pseudotumors, with a significant 60.9% of asymptomatic patients affected.
  • While there was no direct correlation between elevated metal ions and the development of pseudotumors, higher serum cobalt levels were linked to larger pseudotumors and were more prevalent in symptomatic patients.

Article Abstract

The purpose of this study is to quantify the prevalence of pseudotumors in patients with well-functioning and painful metal-on-metal total hip arthroplasty, to characterize the pseudotumor with the use of MARS-MRI, and to assess the relationship between pseudotumors and metal ions. We retrospectively reviewed 102 single surgeon patients. The results showed that 68.6% developed pseudotumor with 60.9% of the asymptomatic group developing pseudotumor. The symptomatic group had a higher proportion of patients with elevated serum cobalt levels (P=0.035). There was no difference found with elevated metal ions and prevalence of pseudotumor, but elevated cobalt levels were associated with larger pseudotumor size (P=0.001). The available evidence indicated that most patients that develop pseudotumors are asymptomatic, and that elevated serum cobalt levels may be associated with symptoms and pseudotumor size.

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http://dx.doi.org/10.1016/j.arth.2015.07.011DOI Listing

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