Fifty-eight patients with recurrent nasopharyngeal carcinoma in nasopharynx and/or regional areas were re-radiated from 1972 to 1979 after initial irradiation. 70.7% of the recurrence appeared within 3 years after initial treatment. 90.9% of the recurrent tumor disappeared after re-radiation. The 3-and 5-year survival rates were 29.3% (17/58) and 12.1% (7/58). The factors influencing the prognosis are: the interval between the treatment and the recurrence; dose of re-radiation; and initial stage of the primary lesions. The authors suggest that the dose of re-radiation should be 70 Gy/7 weeks.
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