Introduction: Elevated serum uric acid (SUA) levels are associated with increased cardiovascular risk.
Objective: To evaluate the association between SUA levels and cardiometabolic parameters.
Materials And Methods: SUA levels and metabolic parameters were evaluated in 139 subjects, divided into low (<5 mg/dl) and high SUA group (≥5 mg/dl).
Results: In low SUA group, SUA levels directly correlated with creatinine, body mass index, waist circumference, blood pressure, glucose and insulin levels, triglyceride and C-reactive protein levels. In high SUA group, SUA levels directly correlated with body weight, triglyceride, C-reactive protein, and inversely correlated with HDL-cholesterol concentrations.
Discussion And Conclusions: High SUA levels were linked with several cardiometabolic parameters, and low SUA levels were linearly correlated with recognized cardiovascular risk factors. Therefore, increasing SUA levels - even at low concentration - could be associated with higher cardiovascular risk. Thus the range of normality for SUA level should be further analysed.
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| http://dx.doi.org/10.3109/13813455.2015.1069359 | DOI Listing |
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