Noninvasive prenatal testing (NIPT) using cell-free DNA is being offered to an increasing number of women. Comprehensive pre-test counseling is complicated by emerging information about the benefits and limitations of testing, as well as the potential to detect incidental findings. Genetic counselors are trained to facilitate informed decision-making; however, not all centers have access to these professionals. To aid in the informed consent process, we have summarized key points to be included in discussions with patients who are considering NIPT.
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http://dx.doi.org/10.1002/pd.4666 | DOI Listing |
Med Sci (Basel)
December 2024
Department of Medical Genetics, Faculty of Medicine, Medical University of Varna, 9002 Varna, Bulgaria.
: NIPT is a widely implemented method for prenatal screening of chromosomal disorders. Its introduction initiated the practice of counseling women pre- and post-analytically. Since the test's usage is established in different conditions, comparing data from various socioeconomic and cultural backgrounds would be of scientific value.
View Article and Find Full Text PDFBMC Cancer
January 2025
Medical and Translational Oncology, Department of Oncology, Azienda Ospedaliera Santa Maria, Viale Tristano Di Joannuccio 1, Terni, 05100, Italy.
Prostate cancer (PCa) ranks among the most prevalent malignancies in men, with notable associations to Hereditary Breast and Ovarian Cancer Syndrome (HBOC) and Lynch Syndrome, both linked to germline likely pathogenetic variant/pathogenetic variant (LPV/PV) in genes involved in DNA repair. Among these genes, BRCA2 in PCa patients is the most frequently altered. Despite progresses, challenges in BRCA carriers detection persist, with a quarter of PCa cases lacking family history.
View Article and Find Full Text PDFFront Psychol
January 2025
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Introduction: The birth and admission of a premature infant to the NICU is often an unexpected experience and a mental and spiritual challenge for families. Spiritual health is an influential factor affecting how a mother faces and endures a stressful situation. Improving the mother's spiritual health requires cognitive therapy approaches, including mindfulness techniques.
View Article and Find Full Text PDFFront Public Health
January 2025
School of Education, Wenzhou University, Wenzhou, China.
Introduction: Due to the acceleration of modern life rhythm, students with developing minds are susceptible to negative external influences, leading to a growing concern for their mental health. Boarding primary school students have limited interaction with relatives compared to their non-boarding counterparts, rendering them more prone to feelings of depression and loneliness, resulting in various negative emotions. Therefore, our study aimed to explore the effects of group counseling interventions on reducing depression and loneliness among adolescents.
View Article and Find Full Text PDFSyst Rev
January 2025
Department of Nursing and Midwifery, Faculty of Health Sciences, Mountains of the Moon University, Fort Portal, Uganda.
Background: HIV-related stigma remains a key barrier to the attainment of the UNAIDS global goal of ending AIDS by 2030. Due to the social and contextual nature of HIV-related stigma, community-based interventions may be more effective in addressing it. In this review, we synthesized evidence on the effectiveness and features of community-based interventions against HIV-related stigma in Sub-Saharan Africa.
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