On the characteristic equation λ = α1 + (α2 + α3λ)e(-λ) and its use in the context of a cell population model.

J Math Biol

Graduate School of Mathematical Sciences, University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo, 153-8914, Japan.

Published: March 2016

In this paper we characterize the stability boundary in the (α1, α2)-plane, for fixed α3 with −1 < α3 < +1, for the characteristic equation from the title. Subsequently we describe a nonlinear cell population model involving quiescence and show that this characteristic equation governs the (in)stability of the nontrivial steady state. By relating the parameters of the cell model to the αi we are able to derive some biological conclusions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751237PMC
http://dx.doi.org/10.1007/s00285-015-0918-8DOI Listing

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