Analysis of published depth-kymography data [George, de Mul, Qiu, Rakhorst, and Schutte (2008). Phys. Med. Biol. 53, 2667-2675] shows that, for the subject studied, the flow due to the longitudinal sweeping motion of the vocal folds contributes several percent of a typical acoustic flow at the larynx. This sweeping flow is a maximum when the glottis is closed. This observation suggests that assumption of zero laryngeal flow during the closed phase as a criterion when determining parameters in inverse filtering should be used with caution. Further, these data suggest that the swinging motion contributes work to overcome mechanical losses and thus to assist auto-oscillation.
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http://dx.doi.org/10.1121/1.4922470 | DOI Listing |
Cureus
December 2024
College of Nursing, Kanto Gakuin University, Yokohama, JPN.
High-flow nasal oxygen therapy (HFNO) is highly versatile and employed in varied situations, including after extubation, in cases of respiratory failure, and at the end of life. However, its impact on swallowing function is not yet elucidated. Therefore, this scoping review aimed to clarify how HFNO affects swallowing function and whether it poses a risk for aspiration pneumonia.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Introduction: Computational fluid dynamics (CFD) is gaining momentum as a useful mechanism for analyzing obstructive disorders and surgeries in humans and warrants further development for application in equine surgery. While advancements in procedures continue, much remains unknown about the specific impact that different surgeries have on obstructive airway disorders. The objective of this study was to apply CFD analysis to an equine head inhalation model replicating recurrent laryngeal neuropathy (RLN) and four surgical procedures.
View Article and Find Full Text PDFFront Oncol
December 2024
Department of Otolaryngology, Longgang Otolaryngology hospital & Shenzhen Key Laboratory of Otolaryngology, Shenzhen Institute of Otolaryngology, Shenzhen, China.
Head and neck squamous cell carcinoma (HNSCC) originates from the mucosal epithelium of the oral cavity, pharynx, and larynx, and is marked by high rates of recurrence and metastasis. Calcium signaling is associated with the progression of HNSCC and the development of drug resistance. Changes in calcium ion flow can trigger severe pathophysiological processes, including malignant transformation, tumor proliferation, epithelial-mesenchymal transition, and apoptosis evasion.
View Article and Find Full Text PDFData Brief
February 2025
Department of Biomedical Engineering, University of Massachusetts, 1 University Ave., Lowell, MA 01854, USA.
This dataset comprises a comprehensive collection of videos and images illustrating the fluid dynamics of swallowing and aspiration in a patient-specific pharyngolaryngeal model with varying epiglottis angles. The data also includes the physical properties of the fluids used, comprising dynamic viscosity, surface tension, and contact angle. Videos under varying swallowing conditions were collected to investigate the mechanisms underlying aspiration.
View Article and Find Full Text PDFBMC Anesthesiol
January 2025
Department of Anesthesiology, The Fourth Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215124, China.
Background: Intravenous anesthesia with high-flow nasal cannula (HFNC) has been reported to benefit oxygen reserves and enhance postoperative recovery in surgeries requiring low neuromuscular blockade. This study investigated whether HFNC improves recovery quality in elderly undergoing ureteroscopic holmium laser lithotripsy (UHLL).
Methods: We enrolled 106 elderly patients undergoing UHLL, with 96 patients (48 per group) included in the final analysis.
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