Introduction: Action On Plastic Surgery (AOPS) criteria for funding of gynaecomastia surgery are: the patient should be post-pubertal, have a BMI ≤ 25 kg/m(2), endocrine and drug causes and breast cancer should be excluded and the patient should demonstrate psychological distress. We evaluated how NHS funding for gynaecomastia surgery varies between Clinical Commissioning Groups (CCGs) in England and whether there is a "postcode lottery".
Methods: The gynaecomastia surgery policies for 211 CCGs in NHS England were reviewed against the AOPS criteria and grouped according to their funding policies: group 1 (if criteria met, funding approved); group 2, (if criteria met, prior approval required); group 3 (no criteria, individual funding request only) and group 4 (no funding).
Results: Policies were available for all CCGs. Fifty-nine (28.0%) CCGs were in group 1, 87 (41.2%) in group 2, 44 (20.9%) in group 3 and 21 (10.0%) in group 4. Of those in groups 1 and 2, five (3.4%) CCGs used all six AOPS criteria. Approximately 70% CCGs with criteria (in groups 1 and 2) stipulated that the patient should be post-pubertal, have a BMI ≤ 25 kg/m(2) and endocrine and drug causes should be excluded. Breast cancer should be excluded in 51.4% and the patient should show psychological distress in 13.7% CCGs. Of those in groups 1 and 2, 118 (80.8%) CCGs specified additional criteria.
Conclusions: CCGs do not use the AOPS criteria uniformly and restrict surgery according to their own criteria. Overall, there is a "postcode lottery" for gynaecomastia surgery within NHS England.
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http://dx.doi.org/10.1016/j.ijsu.2015.07.688 | DOI Listing |
Chemosphere
December 2024
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, 100012, China.
Sulfonamides (SAs) are known for their persistence and have become one of the most frequently detected pharmaceuticals and personal care products (PPCPs) in the environments. The widespread presence of SAs in natural waters, wastewater, soil, and sediment has prompted growing concern due to their potential threats to both human health and ecological systems. Persulfate-based advanced oxidation processes (PS-AOPs) have emerged as a promising technology for effectively mitigating the presence of these pollutants in the environment.
View Article and Find Full Text PDFHeliyon
October 2024
Crop Science Discipline, University of KwaZulu-Natal, Private BagX01, Scottsville, Pietermaritzburg, 3209, South Africa.
Pathogen removal in wastewater offers a chance to recover water and nutrients for crop production, reducing environmental contamination and public health risks. However, the risk of pathogens regrowing in treated effluents can endanger public health if reused in agriculture, attracting stringent reuse standards. While advanced oxidation processes (AOPs) promise to reduce pathogens, eliminating regrowth potential in AOP-treated effluents requires further scrutiny.
View Article and Find Full Text PDFCrit Rev Toxicol
November 2024
Valeo Sciences LLC, Ladera Ranch, CA, USA.
Fiber dimension, durability/dissolution, and biopersistence are critical factors for the risk of fibrogenesis and carcinogenesis. In the modern era, to reduce, refine, and replace animals in toxicology research, the application of test methods is paramount for hazard evaluation and designing synthetic vitreous fibers (SVFs) for safe use. The objectives of this review are to: (1) summarize the international frameworks and acceptability criteria for implementation of new approach methods (NAMs), (2) evaluate the adverse outcome pathways (AOPs), key events (KEs), and key event relationships (KERs) for fiber-induced fibrogenesis and carcinogenesis in accordance with Organization for Economic Co-operation and Development (OECD) guidelines, (3) consider existing and emerging technologies for and toxicity testing for the respiratory system and the ability to predict effects , (4) outline a recommended testing strategy for evaluating the hazard and safety of novel SVFs, and (5) reflect on methods needs for correlation (IVIVC) and predictive approaches for safety assessment of new SVFs.
View Article and Find Full Text PDFChemosphere
October 2024
Key Laboratory of Pollution Process and Environmental Criteria, Ministry of Education, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China; Tianjin Key Laboratory of Environmental Technology for Complex Trans-Media Pollution, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China; Tianjin Advanced Water Treatment Technology International Joint Research Center, College of Environmental Science and Engineering, Nankai University, Tianjin, 300350, China. Electronic address:
In recent years, electrochemical advanced oxidation processes (EAOPs) combined with ozonation have been widely utilized in water/wastewater treatment due to their excellent synergistic effect, high treatment efficiency, and low energy consumption. A comprehensive summary of these ozone-based EAOPs is still insufficient, though some reviews have covered these topics but either focused on a specific integrated process or provided synopses of EAOPs or ozone-based AOPs. This review presents an overview of the fundamentals of several ozone-based EAOPs, focusing on process optimization, electrode selection, and typical reactor designs.
View Article and Find Full Text PDFBackground: Obesity and COVID-19 are at the top of nowadays health concerns with significant crosstalk between each other. The COVID-19 pandemic negatively affected healthy lifestyles and increased obesity prevalence. Thus, there was a surge in anti-obesity products (AOPs) intake.
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