Study Design: Medical economic model with multi-way sensitivity analysis.
Objective: To compare the direct costs of growing rod (GR) versus Magnetic Expansion Control System (MG) from a payer's perspective. We hypothesized that over time the MG will become more cost-effective.
Summary Of Background Data: Traditional GRs provide effective treatment, but require periodic lengthening surgery. MG allows rod lengthening in clinic, but the implant is expensive. The cumulative cost savings are not well understood.
Methods: Index surgery, implant cost, lengthening procedure, and revision surgery due to implant failure or infection were identified as major parameters contributing to the cumulative cost. The "base," "low," and "high" values for the cost and the incidence of each parameter were determined by literature reports, health care database search, or expert consultation. The cumulative cost was compared annually during 5 years of follow-up. Marginal cost was defined as the cost of (GR-MG) for each cumulative year. Final cumulative cost and extreme case scenario at year 5 were assessed by deterministic sensitivity analysis.
Results: MG resulted in higher cumulative cost at years 1 and 2, and became lower cost at years 3 through 5. The marginal cost at year 1 was a negative value of $16K, and trended toward positive values of $12K at year 3 and $40K by year 5. Sensitivity analysis revealed that in extreme case, MG could cost more, shown by a marginal cost of $26K by implementing the extreme values of the 3 parameters carrying highest variance: MG-infection management, GR-revision surgery, and GR-lengthening procedure.
Conclusion: MG achieved cost neutrality to GR at 3 years after index surgery. This is the first medical economic study in the United States comparing the cost of GR versus MG and demonstrates potential cost-effectiveness of MG from payer's perspective if in place for more than 3 years.
Level Of Evidence: 2.
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http://dx.doi.org/10.1097/BRS.0000000000001077 | DOI Listing |
ANZ J Surg
March 2025
General Surgery, Monash Health, Monash University, Melbourne, Victoria, Australia.
Background: Superficial abscess of the skin is a common emergency presentation often requiring surgical management. Ambulatory Care Pathways (ACPs) are a method that can reduce the burden of this disease on hospital bed pressure by treating patients with superficial abscesses as day cases. We conducted a prospective cohort study to assess the safety and effectiveness of an ACP for patients meeting strict criteria with a superficial abscess.
View Article and Find Full Text PDFAnn Allergy Asthma Immunol
March 2025
Division of Allergy, Department of Pediatrics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada; BC Children's Hospital Research Institute, Vancouver, BC, Canada.
Background: Sublingual immunotherapy (SLIT) is a safe, effective therapy for the treatment of food allergy. Studies demonstrating SLIT efficacy have primarily used pharmaceutical glycerinated food extracts for the administration of food allergens, which may limit accessibility due to extract cost and availability.
Objective: To develop novel sample protocols and resources for the preparation of grocery-sourced real food SLIT solutions, which could help more clinicians incorporate food SLIT into their practice and increase accessibility to this treatment.
Diabetes Metab Syndr Obes
March 2025
Health Management Ctr, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Objective: To evaluate the predictive value of the triglyceride-glucose waist circumference index (TyG-WC) for hyperuricemia (HUA) risk in the hypertensive population.
Methods: This prospective cohort study involved 831 hypertensive patients with normal uric acid levels, who underwent continuous health examinations for five years. Participants were categorized into four groups based on baseline TyG-WC quartiles, and the incidence of hyperuricemia was monitored in each group.
Purpose: Health policy simulation models incorporate disease processes but often ignore social processes that influence health outcomes, potentially leading to suboptimal policy recommendations. To address this gap, we developed a novel decision-analytic modeling framework to integrate social processes.
Methods: We evaluated a simplified decision problem using two models: a standard decision-analytic model and a model incorporating our social factors framework.
Tremor Other Hyperkinet Mov (N Y)
March 2025
Department of Neurology, Consorci Sanitari de Terrassa, Barcelona, Spain.
Background: Essential tremor (ET) presents therapeutic challenges as oral therapies, are often partially effective and carry adverse effects. Deep Brain Stimulation and High-intensity Focused Ultrasound targeting the ventral intermediate thalamic nucleus show efficacy in managing ET; however, their cost and invasiveness deter some patients. Botulinum toxin infiltrations for ET in the upper limbs have been limited by adverse effects.
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