AI Article Synopsis
- The study explored noninvasive treatment of early bleb leaks after trabeculectomy using cyanoacrylate tissue glue (CATG) in three patients.
- All patients experienced bleb leaks shortly after surgery, with varying timeframes for each case.
- CATG proved effective in sealing the leaks, and despite low intraocular pressure and some discomfort, no severe complications were reported, suggesting CATG as a promising option for this type of post-surgery issue.
Article Abstract
We demonstrated a noninvasive management of early bleb leak following trabeculectomy using cyanoacrylate tissue glue (CATG). Three patients who underwent augmented trabeculectomy with mitomycin C with early bleb leak between January 2009 and June 2010 were reviewed. Case 1 and Case 2 exhibited bleb leak on postoperative Day 1 and Case 3 showed leak on follow-up at postoperative Day 7. Case 1 was successfully sealed with CATG at postoperative Day 3, after failed pressure padding and bandage contact lens. Case 2 was successfully sealed with CATG at postoperative Day 3, after failed pressure padding and conjunctiva flap resuturing. In Case 3, the leaking conjunctival flap was managed with combined techniques of resuturing and applying CATG at postoperative Day 9, after failed pressure padding. During leakage, the intraocular pressure was low (6-8 mmHg) in all three cases, with shallow anterior chamber depth and absence of other complications such as choroidal detachment, hypotony maculopathy, or endophthalmitis. Foreign body sensation was the main complaint following the procedure. No clinical allergy reaction was documented. CATG may serve as a potential adjunctive and effective method in the management of posttrabeculectomy early bleb leak.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516338 | PMC |
| http://dx.doi.org/10.2147/IMCRJ.S83821 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Short-Term Outcomes of a Modified Safer Surgery Trabeculectomy Technique.
J Curr Ophthalmol
October 2024
Department of Glaucoma, The Eye Foundation, Coimbatore, Tamil Nadu, India.
Purpose: To determine the short-term outcomes of a modified Moorfields Safer Surgery System technique of trabeculectomy.
Methods: This is a prospective interventional study. Trabeculectomy was performed according to the author's modification of Moorfields Safer Surgery System.
Imaging Anatomy of the Cerebrospinal Fluid Spaces.
Neuroimaging Clin N Am
February 2025
Division of Neuroimaging and Neurointervention, Department of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
The cerebrospinal fluid spaces of the spine and brain are an intricate network of tissues with complex anatomic relationships. Understanding the normal imaging anatomy and variants of these spaces is crucial for accessing the spinal subarachnoid space and evaluating patients with suspected CSF leaks. This article reviews the imaging anatomy of the cerebrospinal fluid spaces in the spine and brain with emphasis on clinically relevant anatomy for percutaneous needle access to the spinal subarachnoid space and management of patients with CSF leak.
View Article and Find Full Text PDFConjunctival Collagen Cross-Linking for the Treatment of Leaking Avascular Cystic Bleb.
Turk J Ophthalmol
October 2024
University of Health Sciences Türkiye, Ulucanlar Eye Training and Research Hospital, Clinic of Ophthalmology, Ankara, Türkiye.
Trabeculectomy is a primary surgical procedure used to reduce intraocular pressure (IOP) in patients with glaucoma. Despite its effectiveness, it can lead to significant complications, including hypotony, choroidal effusion, blebitis, and bleb leaks. Bleb leaks require prompt medical or surgical intervention to prevent severe complications such as blebitis and bleb-associated endophthalmitis.
View Article and Find Full Text PDFInterim Results of the Phase III Portal Extension Trial of the Port Delivery System with Ranibizumab in Neovascular Age-Related Macular Degeneration.
Ophthalmol Retina
August 2024
Genentech, Inc., South San Francisco, California; Byers Eye Institute, Stanford University, Palo Alto, California.
Objective: The Port Delivery System with ranibizumab (PDS) is approved in the United States for neovascular age-related macular degeneration (nAMD). Portal (NCT03683251) is evaluating long-term safety and tolerability of the PDS in patients with nAMD who completed the phase II Ladder (NCT02510794) or phase III Archway (NCT03677934) trials.
Design: Multicenter, nonrandomized, open-label, extension clinical trial.
Oral doxycycline for early bleb leak after trabeculectomy: A case report and review of literature.
Oman J Ophthalmol
October 2023
Dr. Rajendra Prasad Centre for Ophthalmic Sciences, Glaucoma Service, All India Institute of Medical Sciences, New Delhi, India.
We report the adjuvant role of oral doxycycline therapy for the management of early bleb leaks post mitomycin-augmented trabeculectomy. Two glaucoma patients, who underwent trabeculectomy with mitomycin C, presented with a low intraocular pressure (IOP) in the early postoperative period. Both patients had moderately elevated bleb with Seidel's positive test.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!