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Amniotic Fluid Embolism After Cervical Ripening.
Cureus
December 2024
Obstetrics, Orlando Regional Medical Center, Orlando, USA.
Article Synopsis
- Amniotic fluid embolism (AFE) is a rare but severe complication during childbirth that can lead to rapid failure of multiple organ systems and significant maternal mortality.
- A case study involving a 31-year-old woman induced for labor revealed AFE's unpredictability, as she developed sudden fetal distress and hypoxia, leading to an emergency cesarean delivery.
- Despite the high mortality associated with AFE, both the mother and the infant survived and were doing well six months later, highlighting the importance of prompt diagnosis and treatment options like the "A-OK" protocol.
Intravascular Ultrasound Guiding Percutaneous Coronary Interventions in Complex Higher Risk-Indicated Patients (CHIPs): Insight from Clinical Evidence.
Rev Cardiovasc Med
December 2024
Department of Cardiology, Sir Run Run Hospital, Nanjing Medical University, 211112 Nanjing, Jiangsu, China.
Intravascular ultrasound (IVUS) in percutaneous coronary intervention (PCI) has transformed the management of complex higher risk-indicated patients (CHIPs), representing a pivotal advancement in high-risk procedure navigation. IVUS, complementing conventional angiography, provides unparalleled insights into lesion characteristics, plaque morphology, and vessel structure, enhancing the precision of stent placement and postprocedural care for CHIPs. The ongoing trials underscore the pivotal role of IVUS in optimizing procedural accuracy and improving clinical outcomes for high-risk patients, promising exciting new findings.
View Article and Find Full Text PDFTracheal reconstructive surgery under ECMO for the treatment of congenital tracheal stenosis in the premature infant: case report.
Front Pediatr
December 2024
Department of Neonatal Intensive Care Unit, The First Affiliated Hospital of Zhengzhou University, Henan, China.
Background: Congenital tracheal stenosis (CTS) is a rare but life-threatening malformation of the trachea. Surgical reconstruction is the treatment of choice in symptomatic cases which is highly risky and is rarely performed in extremely premature infants. With this, reporting a case of CTS managed by tracheal reconstructive surgery under ECMO in a baby weighing 1.
View Article and Find Full Text PDFHeparin in sepsis: current clinical findings and possible mechanisms.
Front Immunol
December 2024
Department of Critical Care Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immunity and other systems. Coagulation activation is an initial factor for sepsis to develop into multiple organ dysfunction. Therefore, anticoagulant therapy may be beneficial for sepsis patients.
View Article and Find Full Text PDFDeep profiling deconstructs features associated with memory CD8 T cell tissue residence.
Immunity
January 2025
Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address:
Tissue-resident memory CD8 T (Trm) cells control infections and cancer and are defined by their lack of recirculation. Because migration is difficult to assess, residence is usually inferred by putative residence-defining phenotypic and gene signature proxies. We assessed the validity and universality of residence proxies by integrating mouse parabiosis, multi-organ sampling, intravascular staining, acute and chronic infection models, dirty mice, and single-cell multi-omics.
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