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Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of Missouri, Columbia, MO, USA.
Background: The link between stroke and Alzheimer's disease (AD) is recognized. However, the underlying mechanisms are not yet clear. This study seeks to determine if increased AD risk is linked to gut dysbiosis caused by acute ischemic stroke.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
University of Massachusetts Chan Medical School, Worcester, MA, USA.
Background: It has been shown that dysbiosis, or dysfunction of the gastrointestinal (gut) microbiome is associated with Alzheimer's disease (AD). Here, we aimed to expand on beyond our previously reported findings of the gut microbiome associating with AD and explore if the gut microbiome is predictive of cognitive performance in individuals with AD. We sought to identity what cognitive domains are associated with the microbiome in our cohort of AD patients and healthy controls without dementia.
View Article and Find Full Text PDFEstablishment of permanent peritoneal PleurX catheter as palliative treatment of malignant ascites.
Dan Med J
November 2024
Department of Gastrointestinal Surgery, Aarhus University Hospital.
Introduction: Refractory malignant ascites (RMA) is a manifestation of end-stage cancer disease with a major impact on quality of life due to the symptom burden and need for repeated hospitalisations. We previously described the implantation of the permanent PleurX catheter as a treatment of RMA. The present study aimed to evaluate and describe our experience with the permanent PleurX catheter system in the largest cohort to date.
View Article and Find Full Text PDFToll-like receptor 4 plays a vital role in irritable bowel syndrome: a scoping review.
Front Immunol
January 2025
Department of Pediatrics, West China Second University Hospital of Sichuan University, Chengdu, China.
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disease. Recently, an increasing number of studies have shown that Toll-like receptor 4 (TLR4), widely distributed on the surface of a variety of epithelial cells (ECs) and immune sentinel cells in the gut, plays a vital role in developing IBS.
Objectives: We sought to synthesize the existing literature on TLR4 in IBS and inform further study.
Lethal Gastrointestinal Manifestation and 3D-Reconstructive CT in Systemic Polyarteritis Nodosa (PAN).
Int J Rheum Dis
January 2025
Department of Medicine (Rheumatology), Hospital Raja Permaisuri Bainun, Ipoh, Perak, Malaysia.
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