Determination of platelet aggregation and disaggregation and the use of coagulogram indices reflecting the main stages of blood coagulation (the levels of fibrinogen and soluble complexes of fibrin-monomer, fibrinolytic activity) are recommended for the diagnosis of chronic DIC-syndrome in patients with diabetes mellitus. This syndrome is noted in diabetic patients before the development of clinical symptoms of microangiopathy but in parallel with microcirculatory disorders according to the results of conjunctival biomicroscopy. Platelet aggregation indices show correlation with the conjunctival index in diabetic patients even before the development of a clinical picture of diabetic retinopathy.
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