Melioidosis is due to Burkholderia pseudomallei and is known to be endemic in South-East Asia, while epidemiology of disease in Sub-Saharan Africa is still unclear. Prompt recognition of infection is crucial for adequate antibiotic treatment. Infection can lead to visceral abcesses and awareness of this complication is important for proper management.
Download full-text PDF |
Source |
---|
Indian J Microbiol
December 2024
Spine Surgery, Apollo Multispecialty Hospital, Kolkata, India.
Melioidosis rarely presents with spinal involvement, which may lead to neurological complications. It's endemic to Thailand and Australia, but rare in India. Patients with diabetes, immunocompromised states, and chronic renal failure are at high risk of developing melioidosis, which can present with localized or disseminated abscess collection.
View Article and Find Full Text PDFInt J Infect Dis
January 2025
Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia; Infectious Diseases Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Trimethoprim/sulfamethoxazole is the first-line agent for oral eradication therapy for melioidosis but has been associated with toxicity in this context. This study aimed to quantify adverse drug reactions (ADRs) to trimethoprim/sulfamethoxazole when used for treatment of melioidosis, and assess risk factors for ADR development. A retrospective review of antimicrobial associated ADRs was performed in all patients treated for melioidosis in the Northern Territory of Australia from January 2017-September 2022.
View Article and Find Full Text PDFHeliyon
September 2024
The Department of Renal Transplantation, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Melioidosis is a fatal infectious disease caused by . Its clinical manifestations are so varied that it has been called a great mimic. The primary melioidotic prostatic disease usually presents as an abscess of the prostate.
View Article and Find Full Text PDFIDCases
July 2024
Department of Microbiology and Immunology, Sultan Qaboos University Hospital, Oman.
Melioidosis is an emerging tropical infectious disease in travelers. We present a case of travel related melioidosis in a 65-year-old man with chronic obstructive pulmonary disease and end stage renal disease following a two-week business trip to Thailand and attendance of the Songkran festival. This case emphasizes that vigilance, heightened clinical suspicion, and use of appropriate microbiology diagnostic tools are of paramount importance for a timely diagnosis and successful management.
View Article and Find Full Text PDFTrans R Soc Trop Med Hyg
October 2024
Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal 576104, India.
Background: Septic melioidosis is associated with high mortality in resource-limited settings. The current study aims to find 28-d all-cause mortality predictors within 24 h of admission in melioidosis patients presenting to an emergency department.
Methods: This retrospective cohort study (2018-2022) included melioidosis patients divided into two groups based on their primary outcomes (28-d mortality).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!