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Macular Pigment Changes and Visual Recovery Following Successful Full-Thickness Macular Hole Closure Using the Inverted Flap Technique.
J Clin Med
January 2025
Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Napoli, Italy.
: This study aimed to assess the role of macular pigment optical density (MPOD) in patients with a full-thickness macular hole (FTMH) compared to healthy controls, evaluating postoperative changes in MPOD and exploring potential correlations with visual outcomes. : This prospective, cross-sectional, comparative study included 16 eyes from FTMH patients who achieved anatomical hole closure following pars plana vitrectomy with the inverted ILM flap technique. Each eye underwent a comprehensive ophthalmologic examination, including BCVA and intraocular pressure measurements, anterior segment evaluation, fundus examination, and macular assessment with Enhanced Depth Imaging Optical Coherence Tomography (EDI-OCT, Spectralis, Heidelberg Engineering Inc.
View Article and Find Full Text PDFThe Impact of Polymerized Whey Protein on the Microstructure, Probiotic Survivability, and Sensory Properties of Hemp Extract-Infused Goat Milk Yogurt.
Foods
December 2024
Department of Nutrition and Food Sciences, The University of Vermont, Burlington, VT 05405, USA.
Goat milk yogurt infused with hemp extract (HE) is a novel dairy product; however, the unpleasant flavors from hemp terpenes and goat milk may impact its acceptance and popularity. This study aimed to investigate the effect of polymerized whey protein (PWP) on mitigating the hempy flavor of HE-infused goat milk yogurt and its impact on the physicochemical properties, microstructure, and probiotic survivability. Goat milk yogurt samples were infused with either nothing (plain flavor), HE, HE plus whey protein isolate, or HE plus PWP.
View Article and Find Full Text PDFNeutrophil Extracellular Trap Formation Model Induced by Monosodium Urate and Phorbol Myristate Acetate: Involvement in MAPK Signaling Pathways.
Int J Mol Sci
December 2024
School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Neutrophil extracellular traps (NETs) formation is a key process in inflammatory diseases like gout, but the underlying molecular mechanisms remain incompletely understood. This study aimed to establish a model to examine the formation of NETs induced by monosodium urate (MSU) and phorbol 12-myristate 13-acetate (PMA) and to elucidate their molecular pathways. Laser confocal microscopy was used to visualize NET formation, while flow cytometry was employed to detect reactive oxygen species (ROS) production.
View Article and Find Full Text PDFExperiment and Simulation Study on the Crashworthiness of Markforged 3D-Printed Carbon/Kevlar Hybrid Continuous Fiber Composite Honeycomb Structures.
Materials (Basel)
January 2025
Key Laboratory of Testing Technology for Manufacturing Process of Ministry of Education, Southwest University of Science and Technology, Mianyang 621010, China.
Article Synopsis
- Fiber hybridization helps address brittle fractures in composite honeycombs, but different fiber interactions create complex failure mechanisms.
- Researchers 3D-printed honeycomb composites using carbon and Kevlar fibers to study their structural failure through experiments and simulations.
- Results showed that carbon/Kevlar composites had the best energy absorption and cost-effectiveness, while CFRP had the highest load capacity; the presence of Kevlar led to ductile failure, contrasting with the brittle failure seen in Onyx honeycombs.
A Method for Determining the Fracture Toughness of Shotcrete Materials Subjected to Freeze-Thaw Cycles.
Materials (Basel)
January 2025
School of Civil Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Defects can be introduced into shotcrete materials after a few freeze-thaw cycles, which has a significant influence on the fracture performance of shotcrete. In this study, a series of shotcrete specimens with varying sizes, geometries, and initial crack lengths were prepared to investigate the fracture properties of notched shotcrete under freeze-thaw conditions. Considering the effects of specimen boundaries and material microstructure, a linear closed-form solution was proposed to determine the fracture toughness of frost-damaged shotcrete.
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