Expedited Partner Therapy (EPT) is the practice of treating the partners of patients with sexually transmitted infections by providing medications for the patient to deliver to his or her sexual partner (s) without direct clinical assessment of the partner(s). EPT is an evidence-based option that can augment existing partner management strategies. For military health care providers, questions still loom as to the pragmatic medical, legal, and ethical uncertainties of EPT use in military populations. These issues, in addition to the absence of an explicit Department of Defense EPT policy may dissuade military clinicians from fully employing EPT to prevent reinfection and inhibit additional disease transmission in their patients. To advance the notion that EPT could not only be an efficient but also a vital measure to decrease the high sexually transmitted disease burden, this report highlights existing approaches utilized by military providers to treat partners of patients diagnosed with chlamydia and/or gonorrhea, benefits of using EPT in military populations, and specific challenges of implementing an EPT program. This report asserts that now is the time to "push the conversation" on the use of EPT as a viable choice for military providers.
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http://dx.doi.org/10.7205/MILMED-D-14-00590 | DOI Listing |
BMC Cancer
January 2025
Department of Medical Oncology, Cancer Centre of Excellence, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited treatment options yielding poor outcomes. This study aimed to evaluate the real-world clinical characteristics, treatment patterns, and outcomes of patients with locally advanced unresectable and de-novo metastatic PDAC in Saudi Arabia, providing regional data to compare with international benchmarks.
Methods: This is a retrospective, multicentre study involving 350 patients diagnosed with unresectable locally advanced or de-novo metastatic PDAC between January 2015 and November 2023.
J Gen Intern Med
January 2025
Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, USA.
Background: In the United States (U.S.), the prevalence of anxiety and depression is increasing, yet significant barriers to mental health treatment remain.
View Article and Find Full Text PDFJ Head Trauma Rehabil
January 2025
Author Affiliations: Department of Rehabilitation Medicine, University of Washington, Seattle, Washington (Drs Bale and Hoffman); and Craig Hospital Research Department, Englewood, Colorado (Mr Sevigny).
Objective: To determine whether there are differences in healthcare utilization for chronic pain based on location (rural vs urban/suburban) or healthcare system (civilians vs Military Service Members and Veterans [SMVs]) after moderate-severe TBI.
Setting: Eighteen Traumatic Brain Injury Model Systems (TBIMS) Centers.
Participants: A total of 1,741 TBIMS participants 1 to 30 years post-injury reporting chronic pain at their most recent follow-up interview.
Alzheimers Dement
December 2024
Huashan Hospital, Fudan University, Shanghai, Shanghai, China.
Background: Alzheimer's disease (AD) is a devastating neurological disease with complex genetic etiology, yet most known loci were only identified from the late-onset type of European ancestry.
Method: We performed a two-stage genome-wide association study (GWAS) of AD totaling 6,878 Chinese and 487,511 European individuals.
Result: We demonstrated a shared genetic architecture between early- and late-onset AD.
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