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Toluene-2,5-Diamine Sulfate: Allergen of the Year 2025.
Dermatitis
January 2025
Department of Dermatology, University of California, San Francisco, California, USA.
Toluene-2,5-diamine sulfate (PTDS), also known as toluene diamine sulfate or 2,5-diaminotoluene sulfate, is an aromatic amine that can be used as a paraphenylenediamine (PPD) hair dye alternative. Patients may develop contact allergy to PTDS, and it is often omitted from standard patch test screening series, possibly leading to underdiagnosis. The American Contact Dermatitis Society named PTDS the Allergen of the Year for 2025, aiming to raise awareness of its dual role as both an allergen and an alternative for some PPD-allergic individuals.
View Article and Find Full Text PDFBerberrubine protects against cisplatin-induced ototoxicity by promoting folate biosynthesis.
Front Pharmacol
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Department of Otolaryngology-Head and Neck Surgery, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Objective: This research investigated the possible shielding properties of BB (Berberrubine) against the harmful auditory effects of cisplatin, preliminarily delving into the underlying mechanisms responsible for this protection.
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Severe Allergic Contact Dermatitis to Hair Dye in a Patient With Atopic Dermatitis During Dupilumab Therapy.
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School of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan.
Matrix-assisted laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) is an analytical technique used for the spatial mapping of drugs, explosives, and organic samples, making it a game-changer in Forensic examination. It detects a wide range of biomolecules in their native state without specific tags, antibodies, labels, and dyes. This review aims to highlight the advancement of MALDI-MSI over time and its impact on Forensic Science due to high-resolution molecular imaging.
View Article and Find Full Text PDFType I Hypersensitivity due to Basic Blue 99 in a Hair Colour Conditioning Agent.
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Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
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