Oropharyngeal Carriage of Meningococcus in Portugal by Group and Clonal Complex 6 Years After Adolescent Vaccine Campaign.

Pediatr Infect Dis J

From the *Infectious Diseases Unit and Emergency Service, Hospital Pediátrico de Coimbra, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; †Faculty of Medicine, Universidade de Coimbra, Coimbra, Portugal; ‡Schools of Clinical Sciences and Cellular and Molecular Medicine and §School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; and ¶Vaccine Evaluation Unit, Public Health England, North West, Manchester, United Kingdom.

Published: November 2015

Portugal introduced (2+1) conjugate Meningococcal group C vaccine in 2006 with high coverage catch up to 18 years and has given only 1 dose at 1 year since 2012. Among 601 student oropharyngeal swabs, meningococcal carriage rate was 13.3% (A-0%, B-5.3%, C-0.3%, W-0.2%, X-0.2% and Y-1.7%). C and W strains were of potentially disease-causing clonal complexes (cc) but not the hyperinvasive cc11.

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Source
http://dx.doi.org/10.1097/INF.0000000000000860DOI Listing

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