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Quantitative analysis of the myelin g-ratio from electron microscopy images of the macaque corpus callosum. | LitMetric

AI Article Synopsis

  • The study conducts a thorough morphometric analysis on eight transmission electron micrographs from the corpus callosum of a cynomolgus macaque.
  • It includes raw images and analyzes the distributions of axon caliber and myelin g-ratio.
  • The findings explore the relationship between axon caliber and g-ratio, comparing them to metrics from a related study on myelin g-ratio using MRI.

Article Abstract

We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled 'In vivo histology of the myelin g-ratio with magnetic resonance imaging' (Stikov et al., NeuroImage, 2015).

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510539PMC
http://dx.doi.org/10.1016/j.dib.2015.05.019DOI Listing

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