Objective: To isolate and identify the phenylpropanoids from Saussurea hieracioides.
Methods: The compounds were isolated by chromatographic and their structures were elucidated on the basis of spectra data.
Results: Seven compounds were isolated and identified as umbelliferone (1), scopoletin(2), caffeic acid (3), esculetin (4), skimmin (5), scopolin (6) and chlorogenic acid (7), respectively.
Conclusion: Compounds 3, 4 and 7 are isolated from this plant for the first time.
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Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK. Electronic address:
Infections caused by antibiotic-drug-resistant microorganisms are a major global health concern, and they result in millions of deaths every year. Methicillin-resistant Staphylococcus aureus (MRSA) is one of such drug-resistant microbial strains, and new and effective antimicrobial agents are desperately needed to combat infections caused by MRSA. In the search for effective anti-MRSA agents, the leaves of Citrus grandis (Rutaceae), also known as C.
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