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Granulomatous reaction to red tattoo pigment treated with allopurinol. | LitMetric

Granulomatous reaction to red tattoo pigment treated with allopurinol.

J Cosmet Dermatol

Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Published: September 2015

AI Article Synopsis

  • Granulomatous reactions to tattoo ink, particularly from red pigments containing mercury sulfide, often have limited treatment options.
  • Allopurinol, a drug typically used for other disorders, showed promising results in treating a case of granulomatous reaction to red tattoo pigment over a 6-month period.
  • After stopping allopurinol, the lesion recurred, suggesting the need for further research into its effectiveness for treating such reactions.

Article Abstract

Granulomatous reactions to tattoo ink are most commonly associated with mercury sulfide, a component of red pigments. Treatment options show limited results. Allopurinol, an inhibitor of xanthine oxidase, has been reported as a successful alternative treatment to granulomatous disorders, such as sarcoidosis and granulomatous reactions to fillers and tattoos. We report a case of granulomatous reaction to red tattoo pigment treated with allopurinol for 6 months. Good clinical improvement could be noticed during this time. Two months after we stopped the treatment, the lesion recurred. Allopurinol emerges as an important drug for the management of granulomatous reactions caused by tattoo pigments. Based on the significant clinical improvement noticed during its use, we recommend new studies to elucidate all the potential benefits of the use of allopurinol for the treatment of granulomatous reactions to tattoo ink.

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Source
http://dx.doi.org/10.1111/jocd.12149DOI Listing

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