Recent studies of acute lymphoblastic leukemia have identified activating mutations in components of the interleukin-7 receptor complex (IL7R, JAK1, and JAK3). It will be of interest to investigate both JAK1 and JAK3 kinase inhibitors as targeted agents for these leukemias.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545857 | PMC |
| http://dx.doi.org/10.1186/s13045-015-0192-7 | DOI Listing |
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