A recent proposal is that dark matter could be a thermal relic of 3→2 scatterings in a strongly coupled hidden sector. We present explicit classes of strongly coupled gauge theories that admit this behavior. These are QCD-like theories of dynamical chiral symmetry breaking, where the pions play the role of dark matter. The number-changing 3→2 process, which sets the dark matter relic abundance, arises from the Wess-Zumino-Witten term. The theories give an explicit relationship between the 3→2 annihilation rate and the 2→2 self-scattering rate, which alters predictions for structure formation. This is a simple calculable realization of the strongly interacting massive-particle mechanism.
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http://dx.doi.org/10.1103/PhysRevLett.115.021301 | DOI Listing |
Curr Issues Mol Biol
December 2024
Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Canine mammary carcinomas (CMCs) represent the most prevalent form of cancer in female dogs, characterized by a high incidence and mortality rate. C6 ceramide is recognized for its multifaceted anti-cancer properties, yet its specific influence on CMCs remains to be elucidated. Long noncoding RNAs (lncRNAs), now recognized as functional "dark matter" in precision oncology, are particularly intriguing, with 44% of canine lncRNAs exhibiting tissue-specific expression.
View Article and Find Full Text PDFJ Am Chem Soc
December 2024
Department of Chemical Sciences and Center for Advanced Functional Materials, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, West Bengal, India.
Triple-negative breast cancer (TNBC) poses significant treatment challenges due to its high metastasis, heterogeneity, and poor biomarker expression. The N-terminus of an octapeptide NAPVSIPQ () was covalently coupled to a carboxylic acid derivative of Ru(2,2'-bipy) () to synthesize an N-stapled short peptide-Rubpy conjugate (). This photosensitizer (PS) was utilized to treat TNBC through microtubule (MT) targeted chemotherapy and photodynamic therapy (PDT).
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Department of Physics, Kyungpook National University, Daegu 41566, Republic of Korea.
We give for the first time theoretical estimates of unknown rare electron-capture (EC) decay branchings of ^{44}Ti, ^{57}Co, and ^{139}Ce, relevant for searches of (exotic) dark-matter particles. The nuclear-structure calculations have been done exploiting the nuclear shell model with well-established Hamiltonians and an advanced theory of β decay. In the absence of experimental measurements of these rare branches, these estimates are of utmost importance for terrestrial searches of dark-matter particles, such as axionic dark matter in the form of axionlike particles, anapole dark matter, and dark photons in nuclear transitions.
View Article and Find Full Text PDFPhys Rev Lett
December 2024
Department of Astronomy, Cornell University, Ithaca, New York 14853, USA.
We present a new perturbative full-shape analysis of BOSS galaxy clustering data, including the full combination of the galaxy power spectrum and bispectrum multipoles, baryon acoustic oscillations, and cross-correlations with the gravitational lensing of cosmic microwave background measured from Planck. Assuming the ΛCDM model, we constrain the matter density fraction Ω_{m}=0.3138±0.
View Article and Find Full Text PDFmBio
December 2024
Division of Intramural Research, Computational Biology Branch, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Unlabelled: Metatranscriptomics is uncovering more and more diverse families of viruses with RNA genomes comprising the viral kingdom Orthornavirae in the realm Riboviria. Thorough protein annotation and comparison are essential to get insights into the functions of viral proteins and virus evolution. In addition to sequence- and hmm profile‑based methods, protein structure comparison adds a powerful tool to uncover protein functions and relationships.
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