AI Article Synopsis
- The study examined how simplifying the electrophysiological procedure affects outcomes after subthalamic nucleus implantation in Parkinson's disease.
- Microelectrode recordings were used on different numbers of trajectories for two groups, and clinical evaluations were conducted before and six months after surgery.
- Both groups showed significant improvements in movement scores after surgery, and the findings indicate that as the surgical team's experience grows, a simpler procedure may still yield effective results.
Article Abstract
Background: The aim of the present study was to assess the consequences of a simplification of the electrophysiological procedure on the post-operative clinical outcome after subthalamic nucleus implantation in Parkinson disease.
Methods: Microelectrode recordings were performed on 5 parallel trajectories in group 1 and less than 5 trajectories in group 2. Clinical evaluations were performed 1 month before and 6 months after surgery.
Results: After surgery, the UPDRS III score in the off-drug/on-stimulation and on-drug/on-stimulation conditions significantly improved by 66,9% and 82%, respectively in group 1, and by 65.8% and 82.3% in group 2 (P<0.05). Meanwhile, the total number of words (P<0.05) significantly decreased for fluency tasks in both groups. Motor disability improvement and medication reduction were similar in both groups.
Conclusions: Our results suggest that the electrophysiological procedure should be simplified as the team's experience increases.
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