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Robotic Central Pancreatectomy: Patient Selection and Surgical Approach.
Ann Surg Oncol
March 2025
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Central pancreatectomy (CP) is one of the parenchyma-sparing approaches proposed for low-grade tumors. CP has a lower incidence of diabetes compared with distal pancreatectomy, but may harbor risks of positive distal pancreatic margin, inadequate lymph node (LN) removal, and pancreatic fistula from the pancreaticojejunal anastomosis. Given the reported oncologic safety, we selectively perform CP for small pancreatic neuroendocrine tumors (pNETs) that are localized to the pancreatic neck.
View Article and Find Full Text PDFImpact of pre-compression versus non-compression before parenchyma transection in left-sided pancreatic resection on the rate of clinically relevant pancreatic fistula: multicentre randomized clinical trial.
Br J Surg
February 2025
Department of Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.
Background: Previous retrospective studies have demonstrated the effectiveness of parenchymal pre-compression in reducing pancreatic fistula after left-sided pancreatic resection; however, no multicentre RCT has been conducted. The aim of this study was to investigate whether pre-compression reduces grade B/C pancreatic fistula after left-sided pancreatic resection.
Methods: Between 23 March 2021 and 26 January 2023, patients scheduled for left-sided pancreatic resection were enrolled in a multicentre RCT at 13 hospitals in Japan.
Survival Analysis of 4 Different Age Groups of Pancreatic Ductal Adenocarcinoma After Radical Resection From Retrospective Multi-Center Analysis (YPB-003).
Cancer Med
February 2025
Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine Ube, Yamaguchi, Japan.
Aim: This study aimed to investigate the efficacy of radical resection and postoperative adjuvant chemotherapy on the survival benefit in patients with pancreatic ductal adenocarcinoma (PDAC), stratified by age, frailty, and other factors in actual clinical practice.
Methods: We retrospectively analyzed the clinicopathological and follow-up data of 414 patients with PDAC who underwent surgical resection at nine institutions under the Yamaguchi Pancreat/Biliary Disease Study Group, between January 1997 and December 2016. Recurrence-free survival (RFS) and overall survival (OS) were calculated using the Kaplan-Meier method.
A 76-year-old man presented with a pancreatic cystic lesion on magnetic resonance imaging before surgery for bladder cancer. Endoscopic ultrasound(EUS)suggested a malignant tumor such as a neuroendocrine neoplasm, but EUS-fine-needle aspiration was not performed. In addition, a single tumor 10 mm in size was found in the liver(S5), and liver metastasis was suspected.
View Article and Find Full Text PDFA comprehensive study on postoperative complications and postoperative pancreatic fistula in sporadic non-functional pancreatic neuroendocrine tumors: A retrospective cohort study.
Ann Hepatobiliary Pancreat Surg
February 2025
Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Backgrounds/aims: Balancing surgical risks and benefits is crucial for managing non-functional pancreatic neuroendocrine tumors (NF-PNETs). Despite high postoperative pancreatic fistula (POPF) rates, studies on postoperative complications of sporadic NFPNETs are scarce. Thus, this study aimed to investigate postoperative complications and identify risk factors for POPF.
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