Background: Overweight and obesity in Down syndrome (DS) is a common problem. Chile has a high prevalence of DS.
Aim: To determine overweight and obesity rates in students with DS and evaluate the concordance of three different growth charts.
Material And Methods: Seventy nine students with DS aged between 6 and 18 years (56% males), from three different schools, were included. Weight and height were measured and their body mass index (BMI) was calculated. The nutritional diagnosis was made according to BMI. Myrelid SDM/2002, National Center for Health Statistics (NCHS)/2000, World Health Organization (WHO)/2007 charts for people with DS were used.
Results: Thirty percent of participants had hypothyroidism, 22.8% congenital heart disease and 5% asthma. Overweight and obesity rates according to SDM/2002, NCHS/2000 and WHO/2007 were 43, 57 and 66% respectively. The concordance between WHO/2007 and NCHS/2000 was almost perfect, but not with SDM/2002.
Conclusions: A high rate of overweight and obesity was found in this group of children with DS, independent of the charts used or their comorbidities.
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http://dx.doi.org/10.4067/S0034-98872015000400006 | DOI Listing |
Lipids Health Dis
January 2025
Department of Orthopedics, The 921st Hospital of the People's Liberation Army, The Second Affiliated Hospital of Hunan Normal University, Changsha, 410003, People's Republic of China.
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School of Physical Education, Chizhou University, Chizhou, 247000, China.
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January 2025
Department of Endocrinology, Central South University Third Xiangya Hospital, Changsha, China.
Pancreatic β-cell damage is a critical pathological mechanism in the progression of obese type 2 diabetes mellitus (T2DM). However, the exact underlying mechanism remains unclear. We established an obese T2DM mouse model via high-fat diet feeding.
View Article and Find Full Text PDFSci Rep
January 2025
Unit of Biostatistics, Epidemiology and Public Health, Department of Cardio-Thoraco- Vascular Sciences and Public Health, University of Padua, Padua, Italy.
Childhood obesity is a growing global concern due to its long-term health consequences. Yet, more research relying on multiple time-point BMI measurements is warranted to gain further insight into obesity's temporal trends. We aimed to identify BMI trajectories in children aged 2-10 years and evaluate their association with sociodemographic factors.
View Article and Find Full Text PDFAm J Perinatol
January 2025
Center for Advanced Research Training and Innovation, Center for Birth Defects Research, University of Maryland School of Medicine, Baltimore, Maryland.
This study aimed to assess the strengths, limitations, opportunities, and threats presented by diabetes-in-pregnancy. We review the improvements in maternal and fetal mortality since the advent of insulin therapy, evaluate current health challenges, and identify opportunities for preventing increased mortality due to diabetes-in-pregnancy. Prior to 1922, women with type 1 diabetes mellitus (T1DM) of childbearing age were discouraged from becoming pregnant as the maternal and fetal/neonatal mortality rates were extremely high.
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