Serum lipid levels in patients with minor recurrent aphthous ulcers.

Purpose: To evaluate the possible association between minor recurrent aphthous ulcers (RAUs) and plasma lipid levels.

Methods: 85 patients (50 female, 35 male) with minor RAUs and another 80 patients (52 female, 28 male) without minor RAUs were included in the study. Body mass index (BMI), hemoglobin (HB), white blood cells (WBCs), platelets (PLT), glucose (GL), total cholesterol (TCH), triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), creatinine (CR), alanine transaminase (ALT), and aspartate transaminase (AST) levels, as well as the gender and age of the patients in the groups were compared.

Results: Cumulative evaluation showed that HDL was statistically higher in the control group (P < 0.05). Except for WBCs, PLT, TG, and ALT, all parameters were significantly higher in the study group (P < 0.05). Correlations between minor RAUs and investigated parameters were observed with age, BMI, HB, GL, CR, TCH, HDL, LDL, and AST (P < 0.05). If gender was considered and the groups were compared, the greatest differences were seen between the female study group and the female control group (age, BMI, HB, GL, CR, TCH, TG, LDL, ALT; P < 0.05). Correlations were mostly observed between minor RAUs and parameters within the female group (P < 0.05).