AI Article Synopsis
- Developed a straightforward method to convert a specific triquinane derivative into a diindole macrocycle using techniques like Fischer indolization and ring-closing metathesis (RCM).
- Employed RCM as a crucial step to create various spiro-polyquinane derivatives.
- Focused on synthesizing complex chemical structures through efficient transformations, showcasing the versatility of RCM in organic chemistry.
Article Abstract
We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM). Various spiro-polyquinane derivatives have been assembled via RCM as a key step.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505178 | PMC |
| http://dx.doi.org/10.3762/bjoc.11.126 | DOI Listing |
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