Macrolide-resistant Mycoplasma pneumoniae (MRMP) is highly prevalent in Asia and is now being reported from Europe. Few data on MRMP are available in the United States. Using genotypic and phenotypic methods, we detected high-level MRMP in 13.2% of 91 M. pneumoniae--positive specimens from 6 US locations.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517703PMC
http://dx.doi.org/10.3201/eid2108.150273DOI Listing

Publication Analysis

Top Keywords

macrolide-resistant mycoplasma
8
mycoplasma pneumoniae
8
united states
8
pneumoniae united
4
states macrolide-resistant
4
pneumoniae mrmp
4
mrmp highly
4
highly prevalent
4
prevalent asia
4
asia reported
4

Similar Publications

Trends of Mycoplasma genitalium infections in Berlin, Germany, 2017-2023.

J Glob Antimicrob Resist

December 2024

Praxis Prenzlauer Berg, Berlin, Germany.

Objectives: The cell wall-less species Mycoplasma genitalium is a sexually transmitted pathogen with strong tendency to acquire resistance. Current knowledge about trends of resistance rates and differences between the risk population of men who have sex with men (MSM) and heterosexual patients as well as about circulating genotypes in both groups is limited.

Methods: Between August 2017 and December 2023, M.

View Article and Find Full Text PDF

Purpose Of Review: Define the utility of adjunctive macrolide therapy in patients with more severe forms of community-acquired pneumonia (CAP).

Recent Findings: Guidelines recommend adjunctive macrolide therapy as an option for patients with CAP, admitted to the hospital. A large data set collected both retrospectively and prospectively, including several recent randomized controlled trials (RCTs) have shown that adjunctive macrolide therapy can reduce mortality and improve outcomes in patients with severe CAP, more effectively than other alternative therapies.

View Article and Find Full Text PDF

Background New Zealand has among the highest rates of antimicrobial resistance in Mycoplasma genitalium in the world. The aim of this study was to correlate treatment outcomes with 23S rRNA and parC mutations associated with macrolide and fluroquinolone resistance, respectively, in a cohort of sexual health clinic patients. Methods Laboratory and clinical data were collected for patients with M.

View Article and Find Full Text PDF

Massive Deep Venous Thrombosis in a Child with Necrotizing Pneumonia Due to Mycoplasma Pneumonia Infection.

Infect Drug Resist

November 2024

Department of Infectious Disease, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, Zhejiang, People's Republic of China.

Article Synopsis
  • * An 8-year-old boy with macrolide-resistant pneumonia developed thrombosis in critical areas, including the pulmonary artery and larger veins, leading to abdominal pain and dangerous thrombi sizes.
  • * After standard anti-infection and anticoagulation treatments failed to alleviate his symptoms and manage the risk of thrombus detachment, the patient underwent specialized procedures that successfully improved his condition and prevented recurrence, underscoring the importance of early thrombosis recognition in pediatric cases.
View Article and Find Full Text PDF

Objectives: To detect multidrug resistance gene locus mutations in children with pneumonia through targeted high-throughput sequencing and to explore its clinical significance.

Methods: A retrospective analysis was conducted on the clinical data of 2 899 children with pneumonia, who underwent respiratory pathogen-targeted high-throughput sequencing, treated at Hubei Maternal and Child Health Care Hospital between January and December 2023. The patients were divided into a mutation group (=885) and a non-mutation group (=2 014) based on whether there was a mutation in the 23SrRNA macrolide-resistant gene of .

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!