Changes in the distribution of attention among auditory and peripheral visual stimuli were examined in a choice reaction time paradigm. Two variables were manipulated: predictability of stimulus locations and arousal state of subjects. The arousal level of some subjects was raised by occasionally exposing them to brief, mild electric shocks. On most trials either a tone or a light was presented alone (single-stimulus trials). However, on 20% of the trials both a tone and light were presented simultaneously (dual trials). Two dependent variables were used to assess dominance of attention: reaction time (on all trials) and percentage of time each modality was chosen on dual trials. Neither modality was dominant when subjects were in a nonaroused state and stimulus locations were unpredictable. However, peripheral vision dominated when stimulus locations were predictable or when the subjects' level of arousal was raised. The results are discussed with reference to previous research on sensory dominance and on the facilitating or inhibiting effects of auditory stimuli on reaction time.
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http://dx.doi.org/10.1016/0001-6918(89)90031-0 | DOI Listing |
Alzheimers Dement
December 2024
University of Kansas Medical Center, Kansas City, KS, USA.
Background: Evidence in adults without Down syndrome (DS) suggests that exercise during mid-life improves cognitive function and decreases risk of later life dementia. Studies supporting this relationship in adults with DS are limited. The purpose of this study was to examine changes in cognitive function after a 12-mo exercise intervention in adults with DS without dementia.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Toronto, Toronto, ON, Canada.
Background: Driving cessation among people with cognitive impairments (e.g., Mild Cognitive Impairment; MCI) significantly impacts their independence and overall well-being.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Alabama in Huntsville, Huntsville, AL, USA.
Currently, there are no curative treatments for Alzheimer's Disease. It is crucial to develop screening tools that detect early signs of decline, allowing for timely interventions that may impede the progression of cognitive impairment. Neurospective is a mobile application platform designed to facilitate the early detection of cognitive decline, including mild cognitive impairment (MCI) and pre-clinical Alzheimer's disease and related dementias (ADRD).
View Article and Find Full Text PDFComb Chem High Throughput Screen
January 2025
Department of Andrology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, 100700, China.
Background And Aim: As a classical formula to invigorate blood circulation, Huoxue Tongluo Qiwei Decoction (HTQD) can effectively treat hypertensive erectile dysfunction (ED), but its exact mechanism of action is not yet clear. The goal of this research was to explore the potential mechanism of HTQD in improving hypertensive erectile dysfunction in rats through transcriptomics, network pharmacology, and associated animal experimentations.
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Environ Sci Technol
January 2025
College of Natural Resources and Environment, Northwest A&F University, Yangling 712100, China.
Interactions between manganese dioxides (MnO) and dissolved organic matter (DOM) have long been the subject of scientific inquiry. However, the effect of MnO crystallinity on the DOM fate remains unclear. Herein, we comprehensively investigate the adsorption, protection, and mineralization of DOM by MnO with various crystallinities (order of crystallinity: γ-30 < γ-90 < γ-120).
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