We report an extremely rare case of acute myelomonocytic leukemia (M4) with an MLL-ELL fusion gene lacking the PML-RARα rearrangement that transformed from hypergranular acute promyelocytic leukemia (APL) without showing any karyotypic evolution. The treatment was effective with chemotherapy for M4 and idarubicin plus a cytarabine-based chemotherapy protocol without ATRA.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498851 | PMC |
| http://dx.doi.org/10.1002/ccr3.245 | DOI Listing |
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