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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499269PMC
http://dx.doi.org/10.11604/pamj.2015.20.380.6042DOI Listing

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Hirayama disease (HD) is a rare disorder characterized by insidious asymmetric neurogenic atrophy primarily involving the upper extremities. HD most commonly affects adolescent males and has a favorable prognosis for arrest of progression. Electrodiagnostic (EDX) studies show chronic denervation changes in the distal upper extremity muscles.

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Background: Postural tremor is a common clinical situation. Timely and accurate diagnosis is essential for effective treatment. However, clinicians often encounter difficulties distinguishing between essential tremor and other etiologies due to overlapping symptoms and atypical features.

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Article Synopsis
  • This study is a retrospective cohort analysis that investigates how cervical disc degeneration relates to disease progression in patients with Hirayama disease, specifically looking at changes in cervical intervertebral disc space height.
  • Researchers analyzed data from 35 patients with Hirayama disease and 35 healthy controls, focusing on cervical disc grades and intervertebral space heights from the second to the seventh cervical vertebrae.
  • Results showed significant reductions in intervertebral disc height and increased disc degeneration in Hirayama patients, indicating a potential compensatory mechanism at play.*
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Background: Hirayama disease (HD) is characterized by slow progression of muscle atrophy without sensory disturbance in a single upper extremity in adolescent boys. HD can be treated using both conservative measures and surgery. However, the optimal treatment remains controversial.

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