Previous research suggests that anticipating pain at a particular body location prioritizes somatosensory input at that location. The present study tested whether this prioritization effect is limited to somatosensory information (modality-specific hypothesis) or generalizes to other sensory modalities (multisensory hypothesis). Thirty-four students performed tactile and visual Temporal Order Judgment (TOJ) tasks while either expecting a painful stimulus on one of the hands (threat), or expecting no pain stimulus (control). Participants judged the order of either two visual stimuli (visual condition) or two tactile stimuli (tactile condition), one on each hand. Analyses revealed that only in threat trials, participants became aware of stimuli on the threatened hand more quickly as compared to the neutral hand, replicating the prioritization effect. Of particular interest, this effect was not different between the tactile and visual conditions. This suggests that the anticipation of pain results in multisensory prioritization of information at the threatened body location.
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http://dx.doi.org/10.1016/j.concog.2015.07.003 | DOI Listing |
PLoS One
January 2025
Julius Kühn-Institut (JKI), Federal Research Centre for Cultivated Plants, Institute for Epidemiology and Pathogen Diagnostics, Rodent Research, Muenster, Germany.
Small rodents can cause problems on farms such as infrastructure damage, crop losses or pathogen transfer. The latter threatens humans and livestock alike. Frequent contacts between wild rodents and livestock favour pathogen transfer and it is therefore important to understand the movement patterns of small mammals in order to develop strategies to prevent damage and health issues.
View Article and Find Full Text PDFRev Alerg Mex
December 2024
Escola Superior de Ciências da Saúde ESCS Brasília/DF Brazil, Allergy and Dermatology Outpatient Unit at the Hospital Regional da Asa Norte HRAN - SMHN Q 2.
Objectives: To evaluate the prevalence of methylisothiazolinone sensitivity and associated factors in individuals with suspected allergic contact dermatitis.
Methods: Cross-sectional study based on patch tests, including methylisothiazolinone 0.2%, in 286 participants with suspected allergic contact dermatitis, in Brasília/DF, Brazil, between March/2020 and March/2022.
Alzheimers Dement
December 2024
RIKEN Center for Biosystems Dynamics Research, Suita-shi, Osaka, Japan.
Background: In aging societies, neurodegenerative diseases, such as Alzheimer's disease, are receiving attention. These diseases are primary targets for preemptive medicine, emphasizing the importance of early detection and preventive treatment before the onset of severe, treatment-resistant damages. However, there is a lack of comprehensive investigation of lesions and molecular targets in the entire organ, whereas spatial identification of early-stage lesions is potentially overlooked at the single-cell level.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Texas Health Science Center at Houston, Houston, TX, USA.
Background: Structural variants (SVs), genomic alterations exceeding 50 base-pairs, are known for their significant impact on disease pathology. However, the role of SVs in Alzheimer's Disease (AD) remains unclear. Using a novel high-accuracy SV calling pipeline, we analyzed a diverse sample from the Alzheimer's Disease Sequencing Project (ADSP).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, Netherlands.
Background: Young onset dementia (YOD) is characterized by an atypical clinical manifestation, and it is unclear to what extent impairments in everyday functioning are part of this manifestation. This study aims to describe the prevalence and differences of difficulties in instrumental activities of daily living (IADL) in YOD.
Methods: In this cross-sectional study, 394 subjects with sporadic YOD (onset<65 years,mean(M)age 58.
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